Charleston Heart Study, Charleston, South Carolina, 1960-2000 (ICPSR 4050)
Version Date: Jun 3, 2021 View help for published
Principal Investigator(s): View help for Principal Investigator(s)
Paul J. Nietert, Medical University of South Carolina-Charleston; Susan E. Sutherland, Medical University of South Carolina-Charleston; David L. Bachman, Medical University of South Carolina-Charleston; Julian E. Keil, Medical University of South Carolina-Charleston; Peter Gazes, Medical University of South Carolina-Charleston; Edwin Boyle, Medical University of South Carolina-Charleston
Version V4 (see more versions)
Summary View help for Summary
The Charleston Heart Study (CHS) represents data collected over a 41-year period (1960-2000) in order to provide an understanding of the natural progression of aging in a community-based cohort. In 1960 the CHS began enrolling a random selection of community residents who were 35 years of age and older -- including men and women, Black and White. The primary hypothesis of the original study was to investigate racial differences in the manifestation and risk factors for coronary disease. Over the ensuing 40+ years, a variety of outcome measurements were incorporated into the re-examination of the participants, including psychosocial, behavioral, aging, and functional measures. As a longitudinal study, the CHS allows for the study of the risk factors, correlates, and consequences of aging, while simultaneously allowing for exploration of racial disparity in the manifestation of putative risk factors and outcomes. The CHS began with baseline data and added a special cohort of Black men. In subsequent years three separate follow-ups were conducted. The data include death information for respondents and background characteristics (age, race, sex, occupation, education, and marital status).
Citation View help for Citation
Funding View help for Funding
Subject Terms View help for Subject Terms
Geographic Coverage View help for Geographic Coverage
Smallest Geographic Unit View help for Smallest Geographic Unit
Restrictions View help for Restrictions
This collection is restricted-use. Users interested in obtaining these data from NACDA must complete the NAS-NRC Restricted Data Use Agreement form. Users can download this form from the download page associated with this dataset. Completed forms with original signature(s) should be emailed to firstname.lastname@example.org.
Distributor(s) View help for Distributor(s)
Time Period(s) View help for Time Period(s)
Date of Collection View help for Date of Collection
Data Collection Notes View help for Data Collection Notes
The documentation for this collection is available for direct download; the data files are restricted-use and users must complete the data use agreement to access the data.
Study Purpose View help for Study Purpose
To provide an understanding of the natural progression of aging in a community-based cohort. The primary hypothesis of the original study was to investigate racial differences (Black and White) in the manifestation and risk factors for coronary disease. As a longitudinal study, the CHS allows for the study of the risk factors, correlates, and consequences of aging, while allowing for exploration of racial disparity in the manifestation of putative risk factors and outcomes.
Study Design View help for Study Design
The study was completed during the course of 6 phases, with each phase containing a unique study design:
Baseline: The baseline data are derived from both a personal interview and a brief physical examination with each participant.
Phase 3 (Additional Cohort): A special cohort of 102 Black men were recruited to fill a void of higher socioeconomic status Black men that resulted from the initial cohort selection in 1960-61. 125 Black men were nominated for inclusion by their peers and resulted in 102 observations. The data are derived from both a personal interview and a brief physical examination with each participant.
Phase 10 (Recall 3): Returning subjects participated in an in-home interview with one of two trained interviewers. Those participants who were unable to be interviewed in person were contacted by telephone or mail. A separate questionnaire was developed for the purpose of self-completion, and is not included in the documentation. For the listed interview, the order of the variables generally follows the questionnaire. The user is cautioned to consider the many skip patterns used in administering the questionnaire.
Phase 11 (Recall 4): Returning subjects participated in part or all of a follow-up study. Parameters included background information; general health information; smoking history; functional disability; a cardiovascular questionnaire; sexual dysfunction; cognitive disability; Raynaud's phenomenon; medication history; serum sample; urinalysis; Holter monitoring; electrocardiograph; cardiovascular history; and physical examination
Phase 12 (Recall 5): Returning subjects participated in part or all of a follow-up study. Parameters included serum sample; urinalysis; blood pressure; hearing and visual screening; cognitive disability; walking test; medical history; physical exam; and questionnaires covering background information, general health, smoking history, functional disability, physical ability, cardiovascular health, sexual dysfunction, depression, coffee consumption, medication history, and nutrition
Deaths: data sources included the National Death Index and death certificates. Birthdates were obtained from several sources including follow-up surveys, death certificates, and internet resources. Study participants not confirmed deceased have a date of last contact provided.
Sample View help for Sample
Clustered geographical probability sample.
Time Method View help for Time Method
Universe View help for Universe
Residents of Charleston County, South Carolina in 1960.
Unit(s) of Observation View help for Unit(s) of Observation
Data Type(s) View help for Data Type(s)
Mode of Data Collection View help for Mode of Data Collection
Description of Variables View help for Description of Variables
DS1: Baseline Data 2,181 cases, 48 variables
DS2: Phase 3 Additional Cohort Data 102 cases, 38 variables
DS3: Phase 10 (Recall 3) Data 1,040 cases, 253 variables
DS4: Phase 11 (Recall 4) Data 1,022 cases, 531 variables
DS5: Phase 12 (Recall 5) Data 917 cases, 570 variables
DS6: Deaths 2,283 cases, 13 variables
Presence of Common Scales View help for Presence of Common Scales
Original Release Date View help for Original Release Date
Version History View help for Version History
2021-06-03 Materials underwent additional curation to produce data available in all statistical packages.2018-02-15 The citation of this study may have changed due to the new version control system that has been implemented. The previous citation was:
- Nietert, Paul J., Susan E. Sutherland, David L. Bachman, Julian E. Keil, Peter Gazes, and Edwin Boyle. Charleston Heart Study, Charleston, South Carolina, 1960-2000. ICPSR04050-v4. Ann Arbor, MI: Inter-university Consortium for Political and Social Research [distributor], 2021-06-03. http://doi.org/10.3886/ICPSR04050.v4
2010-06-07 The data are restricted, but the documentation files are now available for download.
2008-04-01 Minor edits were made to the metadata. A change was made in the Limited Use Agreement form and the codebook reflects this change.
2005-01-28 ICPSR data undergo a confidentiality review and are altered when necessary to limit the risk of disclosure. ICPSR also routinely creates ready-to-go data files along with setups in the major statistical software formats as well as standard codebooks to accompany the data. In addition to these procedures, ICPSR performed the following processing steps for this data collection:
- Checked for undocumented or out-of-range codes.
The public-use data files in this collection are available for access by the general public. Access does not require affiliation with an ICPSR member institution.