Transportability of Adolescent Sexual Risk Prevention Interventions, United States, 2000-2015 (ICPSR 39158)

Version Date: Aug 20, 2025 View help for published

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David Barker, Brown University

https://doi.org/10.3886/ICPSR39158.v1

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The cost and challenge of running clinical trials in each subpopulation and each setting results in a patchwork of evidence. Often, some interventions are evaluated with trial samples that are distinct in the distribution of potential treatment modifiers. These gaps in understanding can be filled using transportability methods where the subset of trials that evaluate an intervention are used to transport the potential outcome mean for that intervention to the target population. Despite this, transportability analysis suffers from systematic missing data, a missing data problem that is unique to the settings where data comes from multiple sources.

This harmonized dataset was created to evaluate novel transportability methods. It includes data from six trials of adolescent sexual risk prevention. Interventions evaluated include emotion regulation, skills training, family based, and health promotion. Populations studied include adolescents in mental health care (aged 13-18), those in alternative educational placement (aged 12-19), those indicated by school personnel as having mental or behavioral health issues (aged 12-14), and Black and African American adolescents (aged 14-17) that had lived in the urban areas of four major U.S. cities.

Barker, David. Transportability of Adolescent Sexual Risk Prevention Interventions, United States, 2000-2015. Inter-university Consortium for Political and Social Research [distributor], 2025-08-20. https://doi.org/10.3886/ICPSR39158.v1

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Patient-Centered Outcomes Research Institute (PCORI) (ME-2019C3-17875)

City

This data collection may not be used for any purpose other than statistical reporting and analysis. Use of these data to learn the identity of any person or establishment is prohibited. To protect respondent privacy, the data files in this collection are restricted from general dissemination. To obtain these restricted files, researchers must agree to the terms and conditions of a Restricted Data Use Agreement.

Inter-university Consortium for Political and Social Research
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2000 -- 2015
2000 -- 2015
  1. For additional information on the Transportability of Adolescent Sexual Risk Prevention Interventions Study, please visit the Brown University Health website.
  2. Information on the harmonization process, the subset of trials, and scales can be found in the documentation.

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The purpose of this study is to develop and test methods to transport or generalize results from clinical trials to the target population. Assuming an intervention targeting one of these vulnerabilities will be effective across subpopulations that share the vulnerability, data from these trials enables evaluation of the utility of transportation methods.

The research team employed a three-step approach to evaluate the utility of transportation methods:

  1. Created new methods for applying the results of clinical trials with missing data to the larger group of interest.
  2. Tested the new methods on the data that mimic real patient data.
  3. Applied the methods to the six trials of programs for youth at risk for HIV.

The harmonized dataset includes data from six trials focusing on adolescents attending therapeutic schools, undergoing mental health treatment and living with primary caregiver, showing symptoms of emotional or behavior problems or indicate sexual or substance use behavior, and are Black and African American adolescents residing in one of the test cities.

Longitudinal: Cohort / Event-based

Adolescents at risk for HIV.

Individual, Household

The data includes variables about:

  • Psychological treatment
  • Sexual behavior
  • Self-efficacy for condom use
  • Substance abuse
  • Self-harm
  • Emotional self-efficacy
  • HIV knowledge
  • Peer norms
  • Impulsive decision making
  • Parent-child sexual communication
  • Delinquent behavior

Demographic variables include:

  • Race
  • Age
  • Income
  • Education

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2025-08-20

2025-08-20 ICPSR data undergo a confidentiality review and are altered when necessary to limit the risk of disclosure. ICPSR also routinely creates ready-to-go data files along with setups in the major statistical software formats as well as standard codebooks to accompany the data. In addition to these procedures, ICPSR performed the following processing steps for this data collection:

  • Performed consistency checks.
  • Created online analysis version with question text.
  • Performed recodes and/or calculated derived variables.

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Notes