Center for Education and Drug Abuse Research (CEDAR): Etiological and Prospective Family Study in Southwestern Pennsylvania, Baseline and Follow-Up Data, 1990-2014 (ICPSR 33444)
Early Intervention Colorado (EI-CO) Participant Characteristics, Service Use, and Outcomes, Colorado, 2014-2016 (ICPSR 37131)
Part C of the Individuals with Disabilities Education Act authorizes states, with the incentive of federal financial support, to create Early Intervention (EI) systems, which is a primary source of rehabilitation (e.g., physical, occupational, and speech therapy) services for infants and toddlers with, or at risk for, developmental delays. Having worked with two EI Colorado (EI-CO) programs that employed electronic documentation, the researchers sought to leverage their electronic administrative data in order to examine social disparities in EI service use, including specific rehabilitation services.
The dataset for this data archiving project was generated in collaboration with a large, urban EI program in Colorado, a community partner for an NIH/NCMRR R03 study. This academic-community research partnership provided researchers with access to an urban EI program's electronic administrative database; The researchers' goal was to make these data available for further EI research. Therefore, a database was created and a number of variables were derived that could be of importance to EI stakeholders when conducting clinical queries for quality improvement. Examples of derived variables include EI service use intensity (i.e., hours per month) for all EI services, as well as discipline-specific (e.g., physical or occupational therapy) service use. The researchers obtained permission from the partnering EI agency to archive their EI program data through this project.
The dataset included as part of this collection includes 2045 cases for 44 variables; demographic variables include: race, ethnicity, language, sex, age, and developmental condition type.
Midlife in the United States (MIDUS 2): Neuroscience Project, 2004-2009 (ICPSR 28683)
The Neuroscience study is Project 5 of the MIDUS longitudinal study, a national survey of more than 7,000 Americans (aged 25 to 74) begun in 1994. The purpose of the larger study was to investigate the role of behavioral, psychological, and social factors in understanding age-related differences in physical and mental health. With support from the National Institute on Aging, a longitudinal follow-up of the original MIDUS samples [core sample (N = 3,487), metropolitan over-samples (N = 757), twins (N = 957 pairs), and siblings (N = 950)] was conducted in 2004-2006.
The Neuroscience Project of MIDUS 2 contains data from 331 respondents. These respondents include two distinct subsamples, all of whom completed both the Project 1 Survey and the Project 4 biomarker assessment at University of Wisconsin-Madison: (1) longitudinal (n = 223) and (2) Milwaukee (n = 108). The Milwaukee group contained individuals who participated in the baseline MIDUS Milwaukee study, initiated in 2005.
The purpose of the Neuroscience Project was to examine the central circuitry associated with individual differences in affective style that represent a continuum from vulnerability to resilience, and characterize some of the peripheral consequences of these central profiles for biological systems that may be relevant to health. The primary aims were to: (1) characterize individual differences in both emotional reactivity and emotional recovery using psychophysiological measures such as corrugator electromyography and eyeblink startle magnitude, (2) characterize individual differences in brain morphology, in particular amygdala and hippocampal volume, using structural magnetic resonance imaging (MRI), (3) characterize individual differences in activity within the neural circuitry of emotion regulation using both electroencephalography and fMRI, and (4) test the ability of the central indices in this project to predict the comprehensive array of health, cognitive, psychological, social, and life challenge factors assessed in the other MIDUS projects.
To probe individual differences in emotional reactivity and recovery (a key component of regulation) the Neuroscience Project examined both psychophysiological and fMRI measures during the presentation of emotional (positive and negative) and neutral pictures, and these same measures during a post-picture period. The logic of this strategy is that continued activation during the recovery period following a negative stimulus is indicative of poor automatic emotion regulation. Respondents in the Neuroscience Project are a representative subsample of the MIDUS (Midlife in the United States) survey.
National respondents in the Neuroscience Project are a representative subsample of the MIDUS 2 survey sample (#4652).
The raw neuro-imaging data are not available through NACDA/ICPSR; please see the README file for more information about how to obtain them.
Midlife in the United States (MIDUS 3): Neuroscience Project, 2017-2022 (ICPSR 38862)
From 2004-2009, an initial follow-up of the original Midlife Development in the United States samples (MIDUS 2) was conducted with expansion of the protocol to include Neuroscience Project data collection and a sample of Black Americans from Milwaukee, WI. The MIDUS Neuroscience Project performed a second follow-up from 2017-2022 of the MIDUS Main and Milwaukee samples (MIDUS 3) on a subsample of those who completed the MIDUS 3 Survey and Biomarker Projects.
The goal was to examine indices of brain aging, function, and structure with a focus on the brain circuitry associated with individual differences in affective style, and to characterize the peripheral consequences of these central profiles for biological systems that may be relevant to health. The primary aims were to: (1) characterize individual differences in emotional reactivity, recovery, and sustaining processes using corrugator and zygomatic electromyography and eyeblink startle magnitude, (2) characterize individual differences in brain morphology and connectivity using structural magnetic resonance imaging (MRI) and diffusion weighted imaging (DWI) (3) characterize individual differences in functional activity within the neural circuitry of emotion using task and resting state fMRI, (4) calculate brain age, and (5) test the ability of these indices to predict the comprehensive array of health, wellbeing, cognitive, psychological, social, and life challenge factors assessed in other MIDUS projects. To probe individual differences in emotional processes, psychophysiological and fMRI measures of emotional responses to the presentation of negative, positive, and neutral pictures, and these same measures during a post-picture period were examined.
Emotion-influenced memory was assessed at both the psychophysiological and imaging sessions: (1) Free recall of the presented affective pictures at the end of the psychophysiological session. (2) Memory and likeability ratings for neutral faces paired with the affective pictures in the imaging task. Finally, selected tasks from the CANTAB assessed affective biases and cognitive processes important for emotion regulation.