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Texas Longitudinal Study of Adolescent Stress Resilience and Health, 2016-2019 (TLSASR) is a multi-method study examining the effects of naturalistic stressors on adolescents as they enter and proceed through high school. This transitional period often presents adolescents with more and more complex sources of social and evaluative stress. Both stress levels and effectiveness of adolescents' responses can have consequences on their life course trajectories, including contributing to gender and racial/ethnic disparities in adult health and well-being. The TLSASR dataset aims to support researchers pursuing a deeper and more integrative understanding of this critical adolescent developmental period.

The study's data contain multiple waves of collection spanning the fall of 2016 to the spring of 2019. Informed by the biopsychosocial model of human development, the study integrates data from a range of sources and methods each wave/year. This included a survey battery assessing numerous psychological (e.g., stress, mental health, mindset), biological (e.g., height, weight, pubertal development), and contextual (e.g., school climate) factors, as well as daily in-school experience sampling, and daily salivary hormone levels for hormonal assessment. School records for each year are also included, as is an experimental manipulation testing the effects of a brief growth mindset intervention to promote improved stress resilience.