Advancing Virtual Reality-Based Attentional Bias as a Biomarker for Tobacco Use Disorder, San Diego, California, 2024-2025 (ICPSR 39816)
Version Date: Apr 13, 2026 View help for published
Principal Investigator(s): View help for Principal Investigator(s)
Kelly E. Courtney, University of California-San Diego;
University of California-San Diego
https://doi.org/10.3886/ICPSR39816.v1
Version V1
Summary View help for Summary
The Varenicline Virtual Reality Study includes daily cigarette users, ages 22+, from the San Diego community. Participants are assessed on the VR Nicotine Cue Exposure paradigm then pseudo-randomized (stratified on age and sex) to receive varenicline (target dose 1mg twice daily) or placebo (target n per group=100; target total N=200). Following eight days of titration, participants are assessed again on the VR Nicotine Cue Exposure paradigm.
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Funding View help for Funding
Subject Terms View help for Subject Terms
Geographic Coverage View help for Geographic Coverage
Restrictions View help for Restrictions
Access to these data is restricted. Users interested in obtaining these data must complete a Restricted Data Use Agreement, specify the reason for the request, and obtain IRB approval or notice of exemption for their research.
Distributor(s) View help for Distributor(s)
Time Period(s) View help for Time Period(s)
Date of Collection View help for Date of Collection
Data Collection Notes View help for Data Collection Notes
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This data collection is ongoing and therefore uploaded data is blinded to randomized drug condition.
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These data are a Fast Track Release and are distributed as they were received from the data depositor. The files have been zipped for release. Users should consult the investigator(s) if further information is needed.
Study Purpose View help for Study Purpose
The purpose of this study is to assess short-term nicotine use behaviors.
Sample View help for Sample
Participants for the study were selected using convenience sampling. Data collection is still ongoing, and the final sample size is not yet determined.
Universe View help for Universe
All individuals aged 22 or older from the San Diego county community who use tobacco cigarettes.
Unit(s) of Observation View help for Unit(s) of Observation
Data Type(s) View help for Data Type(s)
Mode of Data Collection View help for Mode of Data Collection
Description of Variables View help for Description of Variables
This study focuses on nicotine use and includes variables on alcohol, cannabis, and health history. Demographic variables include age, race and income.
Response Rates View help for Response Rates
A total of 106 individuals completed phone screenings. Of these contacts, 14 individuals were enrolled into the study (with 5 medical screen failures, 1 withdrawal before randomization, and 2 scheduled for randomization), 6 participants randomized to study medication (all active, completed, and scheduled to complete).
- The response rate for telephone screenings to enrolled was 13.2 percent.
- The response rate for enrolled participants to randomization was 35.7 percent.
- The response rate for telephone screenings to randomization was 4.7 percent.
Presence of Common Scales View help for Presence of Common Scales
The following scales were used in this study:
- State-Trait Anxiety Inventory (STAI)
- Beck Anxiety Inventory (BAI)
- Beck Depression Inventory (BDI)
- Motivation to Stop Scale (MTSS)
- Brief Wisconsin Inventory of Smoking Dependence Motives (WISDM)
- Tobacco Craving Questionnaire -- Short Form (TCQ-SF)
- Population Assessment of Tobacco and Health - Tobacco Dependence (PATH Tobacco Dependence)
Notes
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