Individualized Assessment and Treatment for Marijuana Dependence: Treatment Mechanisms, United States, 2013-2016 (ICPSR 39044)

Version Date: Aug 12, 2024 View help for published

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Mark D. Litt, University of Connecticut Health Center

https://doi.org/10.3886/ICPSR39044.v1

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Marijuana is the most commonly used illicit drug in the US, but treatment for marijuana dependence is not fully effective. The most effective treatments to date have employed motivational enhancement (MET) plus cognitive-behavioral coping skills treatment (CB) and contingency management (CM) for abstinence. This study was intended to deliver a treatment to enhance coping and self-efficacy to improve marijuana outcomes in the long term. Researchers are explored the idea that more tailored teaching of coping skills may result in improved outcomes for marijuana-dependence than those seen thus far. The Individualized Assessment and Treatment Program (IATP) for marijuana dependent patients employed experience sampling (ES) to determine the strengths and weaknesses of each patient in drug-use situations so that treatment could be tailored accordingly.

Participants were 198 men and women meeting criteria for marijuana dependence and randomly assigned to 9 sessions of treatment in one of 4 treatment conditions: Standardized MET plus CB (SMET-CB); SMET+ CM (SMET-CB-CM); IATP; or IATP + CM (IATP-CM). Patients in all treatments engaged in ES via cell-phone for two weeks prior to treatment, for a weekly period during treatment, for another week after treatment has ended, and for two weekly periods at months 8 and 14. In the IATP conditions, the information gathered from the pretreatment and during-treatment ES periods provided data for a functional analysis of patients' drug use and urges to use. Therapists used the information to address specific cognitions, affects, and behaviors that were adaptive and maladaptive, and tailored a specific coping skills program with the patient. During-treatment experience sampling allowed monitoring of the treatment goals and procedures, making the treatment adaptive. In the SMET-CB conditions the experience sampling data were not used in therapy, but still provides in-vivo measures of drug use and coping skills.

It was hypothesized that IATP conditions would yield significantly better coping skills acquisition than SMET-CB conditions, both at posttreatment and at extended follow-ups, and that change in coping skills would predict better outcomes for the IATP conditions. It was further predicted that the addition of CM to both IATP and SMET-CB would enhance short-term and long-term outcomes. The results would have implications for improved tailoring of treatment to patients' strength and deficits, and for the validity of the training of coping skills for cannabis relapse prevention. The data collected will shed light on the ways in which patients in treatment use coping skills in real-time contexts. Finally, the use of repeated ES periods will allow researchers to determine how treatment impacts thoughts, feelings and behaviors, and how these in turn affect outcome in the long and short term.

Litt, Mark D. Individualized Assessment and Treatment for Marijuana Dependence: Treatment Mechanisms, United States, 2013-2016. Inter-university Consortium for Political and Social Research [distributor], 2024-08-12. https://doi.org/10.3886/ICPSR39044.v1

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United States Department of Health and Human Services. National Institutes of Health. National Institute on Drug Abuse (R01DA012728), United States Department of Health and Human Services. National Institutes of Health (M01 RR06192)

Access to these data is restricted. Users interested in obtaining these data must complete a Restricted Data Use Agreement, specify the reason for the request, and obtain IRB approval or notice of exemption for their research.

Inter-university Consortium for Political and Social Research
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2013-07-01 -- 2016-10-15
2013-07-01 -- 2016-10-15
  1. The data collection are from Self-Report questionnaires, Ecological Momentary Assessment data, and Clinical Interviews.

  2. The researchers use the following measurement tools: SCID-I/P, Addiction Severity Index, Time-Line Follow-Back, Marijuana Problem Scale, Brief Symptom Inventory 18, Coping Strategies Scale, Readiness to Change Questionnaire, Drug Taking Confidence Questionnaire, Marijuana Self-Efficacy Scale, Dispositional Craving Questionnaire, Treatment Utilization Questionnaire (TUQ), and Helping Alliance Questionnaire.

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The purpose of the present study is to determine (1) whether a highly tailored approach will result in a more effective treatment than a more static standardized approach; and (2) determine what mechanisms are at work when patients change their drug use behavior, in both the short and the long term. Answers to these questions will help us develop more effective treatments for marijuana dependence.

For the design information on the study, please refer to the research protocol document.

Sampling was opportunistic. Potential subjects were those wanting treatment and responding to advertisements.

Cross-sectional

Adults with cannabis use disorder

Individual

Of the 336 persons who responded to advertisements and were screened, 316 were eligible according to the eligibility criteria. Most (117) of them lost interest in treatment after screening but prior to randomization, and one more dropped out for other reasons before being randomized. The remaining 198 participants were randomly assigned to treatment. Of the 198, 162 were available at the 14-months follow-up.

For information on scales, please refer to the Research Protocol document.

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2024-08-12

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