Studies
33 resultsMidlife in the United States: Core Sample Mortality Data, 1995-2025
In 1995-1996, the MacArthur Midlife Research Network carried out a national survey of over 7,000 Americans aged 25 to 74 (ICPSR 2760). The purpose of the study was to investigate the role of behavioral, psychological, and social factors in understanding age-related differences in physical and mental health.
With support from the National Institute on Aging, an initial follow-up of the original Midlife Development in the United States (MIDUS) samples was conducted in 2004 (MIDUS 2). The daily stress and cognitive functioning projects were repeated at MIDUS 2; in addition the protocol was expanded to include biomarkers and neuroscience. In 2005, a baseline sample of 592 African Americans from Milwaukee was added to MIDUS to examine health issues in minority populations.
In 2013, a third wave (MIDUS 3) of survey data was collected on longitudinal participants. Data collection for this follow-up wave largely repeated baseline assessments (e.g., phone interview and extensive self-administered questionnaire), with additional questions in selected areas (e.g., economic recession experiences, optimism and coping, stressful life events, and caregiving). A third wave of cognitive functioning data and a second wave of the Milwaukee sample were also collected. Data collection for the daily diary, biomarkers, and neuroscience is ongoing. This dataset includes mortality information for all known MIDUS decedents (N=2,822) from the Core National and Milwaukee samples as of December 2025.
Midlife in the United States (MIDUS Refresher 2): Cognitive Project, 2022-2025
The MIDUS Refresher sample is the second wave of the Midlife in the United States (MIDUS) study. The MIDUS study seeks to understand how factors in the lives of American adults such as working conditions, relationships, health, finances, personal outlooks and individual choices impact health and well-being as individuals age from early adulthood to later life. This second wave of the study with the refresher sample also sought to shed light on how U.S. adults have been impacted by the COVID-19 pandemic and how these experiences are linked with their health, broadly defined.
In 2022-2025, the second wave of cognitive assessments were carried out on the MIDUS Refresher participants who had completed the MIDUS Refresher 2 survey interview. The first part of the assessments consists of the Brief Test of Adult Cognition via Telephone (BTACT) including seven subtests: word list recall immediate, word list recall delayed, backward digit span, number series, counting backward speed, category fluency, and an attention switching reaction time task. The second part consists of the Montreal Cognitive Assessment (MoCA-BLIND), which is newly introduced at the Refresher 2. It is an adapted version of the original MoCA, a rapid screening instrument for mild cognitive dysfunction, and tests seven cognitive domains: attention and concentration, memory, language, conceptual thinking, calculations, and orientation.
Midlife in the United States (MIDUS 3): Milwaukee African American Sample, 2016-2017
In 2005, 592 African Americans from Milwaukee were added to the MIDUS sample to examine health issues in minority populations (for more details, see Midlife in the United States (MIDUS 2): Milwaukee African American Sample [ICPSR #22840]). Respondents were interviewed in their homes using a Computer Assisted Personal Interview (CAPI) survey protocol and asked to complete and return a Self-Administered Questionnaire (SAQ). Afterwards these individuals were eligible for participation in the same research protocol as the national MIDUS 2 sample, including cognitive, daily stress, biomarker, and neuroscience projects.
With support from the National Institute on Aging, a second wave of survey data collection on the Milwaukee sample was begun in 2016. The survey consisted of a 2.5 hour CAPI interview followed by a 45-page mailed SAQ. CAPI survey data was collected for 389 individuals, realizing a 78 percent response rate, adjusted for mortality and other eligibility criteria. Data collection for this follow-up wave largely repeated baseline assessments, with additional questions in selected areas (e.g., economic recession experiences, childhood experience with race, etc.). Following successful completion of the CAPI and SAQ protocols, individuals were eligible for participation in cognitive, daily stress, biomarker, and neuroscience projects.