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In 2011-2014, the MIDUS Refresher study recruited a national probability sample of 3,577 adults, aged 25 to 74, designed to replenish the original MIDUS 1 baseline cohort and paralleling the five decadal age groups of the MIDUS 1 baseline survey [ICPSR 2760]. The MIDUS Refresher survey employed the same comprehensive assessments as those assembled on the existing MIDUS sample, but with additional questions about the effect of the economic recession of 2008-09.

The MIDUS Refresher collection is split into two datasets: Aggregate Data and Coded Text Data. The Coded Text Dataset provides coded responses to open-ended question items in the Aggregate Dataset. The survey data collection (Project 1) [MIDUS, ICPSR 2760] consisted of a 30-minute phone interview followed by two 50-page mailed self-administered questionnaires. Survey data were collected on demographic, psycho-social, and physical and mental health information. This new crosssectional MIDUS sample allows the examination of period effects on health (mental and physical) related to the economic recession by comparing the pre-recession MIDUS 1 sample with the post-recession MIDUS Refresher sample. A further objective of the MIDUS Refresher sample was to strengthen cross-project analyses in MIDUS by increasing the sample sizes available for testing hypotheses dealing with the interplay of key factors (e.g., socioeconomic status, gender, psychosocial factors, biological factors) in mid- and laterlife health. To that end, the MIDUS Refresher sample followed the same multi-disciplinary protocol established in the main MIDUS sample, in that after completing the survey protocol respondents were asked to complete a cognitive assessment by phone (Project 3) [MIDUS 3, ICPSR 36346] and later became eligible to participate in daily diary assessments (Project 2) [MIDUS 2, ICPSR 4652] biomarker assessments (Project 4) [MIDUS 2: Biomarker Project, ICPSR 29282] and neuroscience assessments (Project 5) [MIDUS 2: Neuroscience Project, ICPSR 28683].

The MIDUS Refresher was funded by the National Institute on Aging as two separate but related efforts: The MIDUS Refresher younger decades (MRY), was fielded in November, 2011, and recruited over 2,100 new participants aged 25 to 54; Funding was later added for the MIDUS Refresher older decades (MRO), which was fielded in June, 2013 and recruited over 1,400 new participants aged 55 to 74.

Demographic variables include age, sex, gender, race, religion, and marital status.

The Biomarker study is Project 4 of the Midlife in the United States (MIDUS) longitudinal study, a national survey of more than 7,000 Americans (aged 25 to 74) begun in 1994. The purpose of the larger study was to investigate the role of behavioral, psychological, and social factors in understanding age-related differences in physical and mental health. With support from the National Institute on Aging (NIA), a longitudinal follow-up of the original MIDUS samples [core sample (N = 3,487), metropolitan over-samples (N = 757), twins (N = 957 pairs), and siblings (N = 950)] was conducted in 2004-2006. Guiding hypotheses, at the most general level, were that behavioral and psychosocial factors are consequential for health (physical and mental). A description of the study and findings from it are available on the MIDUS website.

The Biomarker Project (Project 4) of MIDUS 2 contains data from 1,255 respondents. These respondents include two distinct subsamples, all of whom completed the Project 1 Survey: (1) longitudinal survey sample (n = 1,054) and (2) Milwaukee sample (n = 201). The Milwaukee group contained individuals who participated in the baseline MIDUS Milwaukee study, initiated in 2005. The purpose of the Biomarker Project (Project 4) was to add comprehensive biological assessments on a subsample of MIDUS respondents, thus facilitating analyses that integrate behavioral and psychosocial factors with biology. The broad aim is to identify biopsychosocial pathways that contribute to diverse health outcomes. A further theme is to investigate protective roles that behavioral and psychosocial factors have in delaying morbidity and mortality, or in fostering resilience and recovery from health challenges once they occur. The research was not disease-specific, given that psychosocial factors have relevance across multiple health endpoints.

Biomarker data collection was carried out at three General Clinical Research Centers (at UCLA, University of Wisconsin, and Georgetown University). The biomarkers reflect functioning of the hypothalamic-pituitary-adrenal axis, the autonomic nervous system, the immune system, cardiovascular system, musculoskeletal system, antioxidants, and metabolic processes. Our specimens (fasting blood draw, 12-hour urine, saliva) allow for assessment of multiple indicators within these major systems. The protocol also included assessments by clinicians or trained staff, including vital signs, morphology, functional capacities, bone densitometry, medication usage, and a physical exam. Project staff obtained indicators of heart-rate variability, beat to beat blood pressure, respiration, and salivary cortisol assessments during an experimental protocol that included both a cognitive and orthostatic challenge. Finally, to augment the self-reported data collected in Project 1, participants completed a medical history, self-administered questionnaire, and self-reported sleep assessments. For respondents at one site (UW-Madison), objective sleep assessments were also obtained with an Actiwatch(R) activity monitor.

In 1995-1996, the MacArthur Midlife Research Network carried out a national survey of over 7,000 Americans aged 25 to 74 [ICPSR 2760]. The purpose of the study was to investigate the role of behavioral, psychological, and social factors in understanding age-related differences in physical and mental health. The study was innovative for its broad scientific scope, its diverse samples (which included siblings of the main sample respondents and a national sample of twin pairs), and its creative use of in-depth assessments in key areas (e.g. daily diary of stressful experiences [ICPSR 3725] and cognitive functioning [ICPSR 3596]) on a subset of participants. A detailed description of the study and findings generated by it are available at: http://www.midus.wisc.edu

With support from the National Institute on Aging, a follow-up of the original Midlife Development in the United States (MIDUS) sample was conducted in 2004 (MIDUS 2 [ICPSR 4652]). The daily stress and cognitive functioning projects were repeated and expanded at MIDUS 2; in addition the protocol was expanded to include biomarkers and neuroscience.

In 2013 a third wave (MIDUS 3) of survey data was collected on longitudinal participants. Data collection for this follow-up wave largely repeated baseline assessments (e.g., phone interview and extensive self-administered questionnaire), with additional questions in selected areas such as economic recession experiences. Cognitive functioning data were also collected at the same time, while data collection for the daily diary, biomarker, and neuroscience projects commenced in 2017.

MIDUS also maintains a Colectica portal, which allows users to interact with variables across waves and create customized subsets. Registration is required.

Project STRIDE is a three-year research project that examines the effect of stress and minority identity related to sexual orientation, race/ethnicity and gender on mental health. The research describes social stressors that affect minority populations, explores the coping and social support resources that they utilize as they confront these social stressors, and assesses the associations of stress and coping with mental health outcomes including mental disorders and wellbeing. The study also explores the impact of various identity characteristics, such as whether an identity is viewed positively or negatively, or whether it is prominent or not to the relationship of stress and mental health outcomes.

The study, using extensive quantitative and some qualitative measures, is a longitudinal survey of 525 men and women between the ages 18 and 59 who are residents of New York City. Socio-demographic information collected about respondents included age, education, race and Hispanic ethnicity, adopting the measures developed and used by the United States Census Bureau in the United States population survey of 2000. In addition to these items, racial/ethnic identity was also assessed with the question "What is the country of origin related to your or your family's ethnic or national background, if any?" Respondents were allowed to select up to two nations from a comprehensive listing. For the purposes of the study, the instrument also assessed whether or not participants were natives of New York City or migrated as adults. Additional demographic variables include employment status, religion, relationship status, and sexual orientation.

This study is part of the Seek, Test, Treat and Retain (STTR) Collaboration Project involved over twenty studies in the fields of HIV and drug abuse. All studies were independently developed, but were chosen for the collaboration because they focused on one or more steps of the HIV treatment cascade: Seek, Test, Treat and Retain. As part of STTR Collaboration Project, the studies were grouped into Criminal Justice-related studies and Vulnerable Population-related studies. The data collected by these studies included twelve common domains (e.g., Demographic characteristics, Mental Health) in each of which a shared questionnaire or instrument was taken up by the studies and adapted to fit the study.

The data in this study focuses on adult respondents' health status and viral load involving HIV and HCV.

This multi-method study seeks to understand both the factors that contribute to harm reduction workers' occupational stress and those that mitigate it by pursuing the following aims:

Aim 1:

• Understanding occupational stressors and resilience strategies among this population by using semi-structured qualitative focus groups with leaders and workers in harm reduction organizations within Texas.

Aim 2:

• Stress First Aid (SFA) consultants utilized the feedback from the Aim 1 Qualitative Focus Groups to adapt the SFA content for harm reduction. The second aim of the study was to hold a 3-day in person train-the-trainer training on the SFA adapted materials for leaders and workers in harm reduction in Texas. The training was facilitated by SFA consultants. The goal of this initial SFA train-the-trainer session was to test the feasibility and acceptability of adapted SFA/HRW materials and develop cadre of team support champions.

Aim 3:

• A 4-month Field testing of the feasibility, acceptability, and appropriateness of the adapted SFA for leaders and workers in harm reduction. The Field Test included a 2-hour in-person training to introduce SFA concepts and how to use SFA on a day-to-day basis in participant's work life and with coworkers, facilitated by participants in Aim 2 who chose to be champions for the Aim 3 Field Test. Additionally, four virtual monthly learning collaboratives were held as part of the Field Test, designed as monthly touch points to refresh and reinforce the SFA principles and get coaching and feedback around any challenges around using SFA, facilitated by the research study team.
• Evaluating the adapted SFA materials and intervention. Reaction interviews were conducted with 13 participants to supplement the surveys.

Drug use remains a major public health problem among youth in the United States. Effective implementation of evidence-based interventions for youth is critical for reducing the burden of drug use and its consequences. The Michigan Model for Health (MMH) is a universal prevention curriculum that has demonstrated efficacy in reducing adolescent substance use. Fidelity is essential to intervention effectiveness, yet youth rarely receive evidence-based interventions (EBIs) as intended; this is partly due to a poor fit between the intervention and the context. The disconnect between the EBI and context is especially pronounced among underserved and vulnerable populations, including among youth exposed to trauma. Trauma is a potent risk factor for substance use, abuse, and the development of substance use disorders. Consequently, there is a critical need to design and test effective, cost-efficient implementation strategies to optimize the fidelity of school-based drug use prevention to meet better the needs of youth exposed to trauma. The study designed and tested a multi-component implementation strategy to improve intervention-context fit and enhance fidelity and effectiveness.

This study was using a 2-group, mixed method, randomized trial design, this pilot study compared standard implementation (Replicating Effective Programs [REP]) versus enhanced REP to deliver MMH. REP is an implementation strategy bundle that promotes EBI fidelity through curriculum packaging, training, and as-needed technical assistance. Enhanced REP incorporates tailoring of the EBI package and training and deploys customized implementation support (i.e., implementation facilitation). The research focuses on youth at heightened risk of drug use and its consequences due to trauma exposure.

The PATH Study was launched in 2011 to inform the Food and Drug Administration's regulatory activities under the Family Smoking Prevention and Tobacco Control Act (TCA). The PATH Study is a collaboration between the National Institute on Drug Abuse (NIDA), National Institutes of Health (NIH), and the Center for Tobacco Products (CTP), Food and Drug Administration (FDA). For Wave 1 (baseline), the study sampled over 150,000 mailing addresses across the United States to create a national sample of people who do and do not use tobacco.

45,971 adults and youth constitute the first (baseline) wave, Wave 1, of data collected by this longitudinal cohort study. These 45,971 adults and youth along with 7,207 "shadow youth" (youth ages 9 to 11 sampled at Wave 1) make up the 53,178 participants that constitute the Wave 1 Cohort. Respondents are asked to complete an interview at each follow-up wave. Youth who turn 18 by the current wave of data collection are considered "aged-up adults" and are invited to complete the Adult Interview. Additionally, "shadow youth" are considered "aged-up youth" upon turning 12 years old, when they are asked to complete the Youth Interview after parental consent.

At Wave 4, a probability sample of 14,098 adults, youth, and shadow youth ages 10 to 11 was selected from the civilian, noninstitutionalized population (CNP) at the time of Wave 4. This sample was recruited from residential addresses not selected for Wave 1 in the same sampled Primary Sampling Units (PSUs) and segments using similar within-household sampling procedures. This "replenishment sample" was combined for estimation and analysis purposes with Wave 4 adult and youth respondents from the Wave 1 Cohort who were in the CNP at the time of Wave 4. This combined set of Wave 4 participants, 52,731 participants in total, forms the Wave 4 Cohort.

At Wave 7, a probability sample of 14,863 adults, youth, and shadow youth ages 9 to 11 was selected from the CNP at the time of Wave 7. This sample was recruited from residential addresses not selected for Wave 1 or Wave 4 in the same sampled PSUs and segments using similar within-household sampling procedures. This second replenishment sample was combined for estimation and analysis purposes with Wave 7 adult and youth respondents from the Wave 4 Cohort who were at least age 15 and in the CNP at the time of Wave 7. This combined set of Wave 7 participants, 46,169 participants in total, forms the Wave 7 Cohort.

Please refer to the Restricted-Use Files User Guide that provides further details about children designated as "shadow youth" and the formation of the Wave 1, Wave 4, and Wave 7 Cohorts.

Dataset 0001 (DS0001) contains the data from the Public-Use File Master Linkage File (PUF-MLF). This file contains 103 variables and 82,139 cases. The file provides a master list of every person's unique identification number and what type of respondent they were in each wave for data that are available in the Public-Use Files and Special Collection Public-Use Files.

Dataset 0002 (DS0002) contains the data from the Restricted-Use File Master Linkage File (RUF-MLF). This file contains 217 variables and 82,139 cases. The file provides a master list of every person's unique identification number and what type of respondent they were in each wave for data that are available in the Restricted-Use Files, Special Collection Restricted-Use Files, and Biomarker Restricted-Use Files.

Three dashboards describe nonfatal drug overdoses within the United States:

1. DOSE Dashboard: Nonfatal Overdose Syndromic Surveillance Data
2. DOSE Dashboard: Nonfatal Overdose Emergency Department and Inpatient Hospitalization Discharge Data
3. The Fentalog Study: A Subset of Nonfatal Suspected Opioid Overdoses with Toxicology Testing

The Criminal Justice Drug Abuse Treatment Studies 2 (CJ-DATS 2) was launched in 2008 with a focus on conducting implementation research in criminal justice settings. NIDA's ultimate goal for CJ-DATS 2 was to identify implementation strategies that maximize the likelihood of sustained delivery of evidence-based practices to improve offender drug abuse and HIV outcomes, and to decrease their risk of incarceration.

CJ-DATS 2 HIV Services Treatment Implementation in Corrections focused on implementing interventions to address the HIV continuum of care in correctional settings. There are 5 datasets associated with this study.

-Dataset 1 (DS1) contains data aggregated at the correction facility level that examines delivery of HIV services in the experimental and control study groups (215 cases).

-Dataset 2 (DS2) and Dataset 3 (DS3) detail survey responses from correctional staff about how the HIV services were changed and/or implemented at their facilities (DS2 has 68 cases and DS3 has 85 cases).

-Dataset 4 (DS4) contains survey responses from inmates about their perceptions of the HIV services provided at facilities in which they are incarcerated (2,301 cases).

-Dataset 5 (DS5) contains data merged together by the principal investigator from several surveys given to treatment staff, treatment directors, correctional officers and correctional directors. This dataset includes demographic information, staff perceptions of their work environment, perceptions of HIV infected individuals, evaluations of HIV workshops and perceptions of the delivery of HIV services at their facility (385 cases).

These 5 datasets contain a total of 889 variables.

CDC has partnered with community-based organizations (CBOs) for many years to expand the reach of HIV prevention efforts. This partnership is important because CBOs often have access to at-risk populations and maintain relationships with communities to which health departments may not have direct access. Currently, CDC funds approximately 153 CBOs through three program announcements to provide HIV prevention services to the following critical target populations who are at high risk for HIV transmission:

- Young men of color who have sex with men and young transgender persons of color (PS11-1113)

- Racial/ethnic minority communities, MSM, IDU, and HIV-infected persons (PS10-1003)

- Persons at risk for HIV in the Commonwealth of Puerto Rico and the United States Virgin Islands (PS08-803)

In December 2011, CDC developed a National HIV Prevention Program Monitoring and Evaluation (NHM&E) framework for monitoring HIV prevention programs at CBOs across all three program announcements. To address the National HIV/AIDS Strategy (NHAS) and the Division of HIV/AIDS Prevention (DHAP) strategic plan, CDC developed monitoring and evaluation (M&E) questions that align with the goals defined by NHAS and DHAP. The NHM&E reporting requirements for CDC directly funded CBOs began with an in-depth analysis of NHAS goals, DHAP strategic plan goals, program announcement objectives, accumulated experiences from working with CBOs, and lessons learned from those experiences. M&E questions were developed from this analysis and reflect the objectives outlined in the three program announcements. Process indicators were developed to assess the M&E questions, and, lastly, variables were developed to directly measure the process indicators.

The NHM&E reporting requirements provide a new approach to evaluating HIV prevention programs. The focus has shifted to emphasize priority program processes and only collecting data that are needed to answer critical M&E questions. As a result, there is a significant reduction in data reporting burden on CBOs-an approximate 65 percent reduction in reporting requirements. Also, CDC is obtaining a data entry system that allows CBOs to have real-time access to their data to help improve program processes. The new data system will calculate NHM&E process indicators. CBOs will be able to generate reports based on their data.

The Helping Young Smokers Quit (HYSQ) initiative was a multi-phase project that addressed the critical need to disseminate effective, developmentally appropriate cessation programs for young smokers. Phase I identified and described tobacco treatment programs available for youth in the United States, Phase II evaluated smoking secession programs tailored for youth to help understand what works, and Phase III identified factors associated with program sustainability. Phase II collected data from five sources: (1) program participants, (2) program providers, (3) program curricula, (4) organizational leaders, and (5) community leaders and community ordinances.

Program participants were interviewed at baseline, end-of program, 6-month follow-up, and 12-month follow-up. Topics covered by the interviews include age, gender, race, Hispanic origin, language spoken at home, employment, income, religiosity, school enrollment, education level, school grades, height, weight, extracurricular activities, recreation, sports, exercise, aspirations after high school, psychological well-being, alcohol consumption, cigarette use and use of other tobacco products, attitudes about smoking, plans to stop/continue smoking, attempts to quit smoking, reasons for participating in the program, topics/issues covered by the program, opinions about the program, and smoking experience since the beginning of the program. In addition, for each follow-up survey, the participants provided a breath sample for carbon monoxide analysis to validate self-reported quit status.

After the last session of each program delivery, the program providers, such as program leaders and cessation counselors, were interviewed about the content and delivery of the program and the reactions of the participants and themselves to the program as delivered. The program providers also kept attendance records.

Curriculum content was abstracted from program manuals and other materials used in each program.

Organizational leaders of the organizations that offered the programs were surveyed about various aspects of each organization, including the organization's smoking cessation program and the organization's mission, general operations, and smoking-related policies and practices.

Community-level information was collected in two ways: (1) interviews of community leaders representing local health departments, school boards, and juvenile justice offices, and (2) archival research of public ordinances relevant to tobacco and control policies.

Nine data files/datasets constitute the data. Datasets 1-4 contain the participant questionnaire data, carbon monoxide measurement data, and program attendance data. Dataset 5 comprises information about each program and its curriculum, some information about the community in which the program was located, and summary data about enforcement of tobacco-related ordinances. Dataset 6 contains information about about the program providers and each program delivery, including recruitment, logistics, content, and the reactions of providers and participants. Dataset 7 covers administrative aspects of the smoking cessation programs and each offering organization's mission, general operations, and smoking-related policies and norms. Dataset 8 contains information about local and state-level tobacco-related ordinances for every state and local jurisdiction where each program was located, and Dataset 9 condenses the information in Dataset 8 into one summary record for each community. The unit of observation for Datasets 1-4 is the participant, for Datasets 5 and 7 the smoking cessation program/offering organization, for Dataset 6 the program delivery/program cohort, for Dataset 8 the ordinance, and for Dataset 9 the community.

This research investigated the relationship between ascribed characteristics, family resources, personal circumstances, and public policies as these affect the transition to adulthood. The transition to adulthood has been extensively studied during the last four decades using a variety of well-established approaches and methods. Changes in the structure and pace of youth-to-adult transitions have been extensively documented, along with the increasingly complex lives young people lead as they negotiate the transition to adulthood. Relatively less attention has been devoted to the factors leading to these changes, and a variety of public policies related to state economic development efforts, education, and financial support for higher education have yet to be examined in any detail. This project built on the principal investigators' prior work on life course transitions and state economic and political contexts to estimate behavioral models of the late 20th and early 21st century transition to adulthood.

Specifically, this research:

1. Defines and describes the successful transition to adulthood in terms of human capital accumulation, attainment of economic security, and partnership and life satisfaction.
2. Identifies group and individual disparities in successful transitions, defined by ascribed characteristics, family resources, and personal circumstances.
3. Measures the impact of the social and economic environments where these transitions occur and the effects of state structures and policies on the successful transition to adulthood, specifically examining whether the impact of these state policies differs by race/ethnicity, immigrant status, and disability status.

The analysis used discrete hazard modeling and hierarchical generalized linear modeling (HGLM) to build a general model of the transition to adulthood on a wide variety of dimensions (from educational attainment to stable employment in a full-time job, employment in a job with health insurance, to independent residence and life satisfaction) and examined systematic changes in the process leading to adulthood across cohorts and across race/ethnic, immigrant, and disability groups.

The Community Vulnerability and Responses to Drug-User-Related HIV/AIDS, 1990-2013 [96 Metropolitan Statistical Areas, United States] study (CVAR) was a research study of why large United States Metropolitan Statistical Areas (MSAs) vary over time in their vulnerability to HIV/AIDS among drug users and in MSA responses to HIV/AIDS. This collection contains estimates of HIV prevalence among people who injected drugs (PWID) and among sub-populations of PWID. This collection is comprised of ten datasets with differing amounts of variables and provides trend data that describe the following:

• Epidemiologic outcomes including population prevalence of PWIDs and Non-injecting drug users (NIDUs), and particularly their prevalence among youth; and, among PWIDs, HIV prevalence, late-diagnosis HIV cases, and AIDS incidence and mortality.
• Implementation of evidence-based drug-related interventions including drug abuse treatment, syringe exchange, HIV counseling and testing.
• Implementation of non-evidence-based drug-related interventions including incarceration and arrests of drug users.

The collection contains data on the MSA sub-populations including Black, Hispanic, White and "other" race categories. In addition, some statistics are presented in age range categories such as ages 15-29, 30-64 and 15-64.

The AIDS Drug Assistance Program (ADAP) Data Report (ADR) includes two components: the Grantee Report and the Client Report. All ADAPs are required to submit both reports.

The Grantee Report is a collection of basic information about the grantee characteristics and policies. It includes a Programmatic Summary section and an Annual Submission section.

The Client Report (or client-level data) is a collection of one record for each client enrolled in the ADAP. Each record includes the client's encrypted unique identifier, basic demographic data, and enrollment and certification information. A client's record may also include data about the ADAP-funded insurance and medication received, including the costs of these services, as well as HIV clinical information.

The Uniform Facility Data Set (UFDS) was designed to measure the scope and use of drug abuse treatment services in the United States. The survey collects information from each privately- and publicly-funded facility in the country that provides substance abuse treatment as well as from state-identified facilities that provide other substance abuse services. Data are collected on a number of topics including facility operation, services provided (assessment, therapy, testing, health, continuing care, special programs, transitional services, community outreach, ancillary), type of treatment, numbers of clients, and various client characteristics. The main objective of the UFDS is to produce data that can be used to assess the nature and extent of substance abuse treatment services, to assist in the forecast of treatment resource requirements, to analyze treatment service trends, to conduct national, regional, and state-level comparative analyses of treatment services and utilization, and to generate the National Directory of Drug and Alcohol Abuse Treatment Programs and its on-line equivalent, the Substance Abuse Treatment Facility Locator.

The National Survey of Substance Abuse Treatment Services (N-SSATS) is designed to collect information from all facilities in the United States, both public and private, that provide substance abuse treatment. N-SSATS provides the mechanism for quantifying the dynamic character and composition of the United States substance abuse treatment delivery system. The objectives of N-SSATS are to collect multipurpose data that can be used to assist the Substance Abuse and Mental Health Services Administration (SAMHSA) and state and local governments in assessing the nature and extent of services provided and in forecasting treatment resource requirements, update SAMHSA's Inventory of Substance Abuse Treatment Services (I-SATS), analyze general treatment services trends, and generate the National Directory of Drug and Alcohol Abuse Treatment Programs and its online equivalent, the Substance Abuse Treatment Facility Locator.

Data are collected on topics including facility operation, services offered (assessment, substance abuse therapy and counseling, testing, transitional, and ancillary), primary focus (substance abuse, mental health, both, general health, other), hotline operation, Opioid Treatment Programs and medication dispensed, languages in which treatment is provided, type of treatment provided, number of clients (total and under age 18), number of beds, types of payment accepted, sliding fee scale, special programs offered, facility accreditation and licensure/certification, and managed care agreements.

The National Survey of Substance Abuse Treatment Services (N-SSATS) is designed to collect information from all facilities in the United States, both public and private, that provide substance abuse treatment. N-SSATS provides the mechanism for quantifying the dynamic character and composition of the United States substance abuse treatment delivery system. The objectives of N-SSATS are to collect multipurpose data that can be used to assist the Substance Abuse and Mental Health Services Administration (SAMHSA) and state and local governments in assessing the nature and extent of services provided and in forecasting treatment resource requirements, update SAMHSA's Inventory of Substance Abuse Treatment Services (I-SATS), analyze general treatment services trends, and generate the National Directory of Drug and Alcohol Abuse Treatment Programs and its online equivalent, the Substance Abuse Treatment Facility Locator.

Data are collected on topics including facility operation, services offered (assessment, substance abuse therapy and counseling, pharmacotherapies, testing, transitional, ancillary), primary focus (substance abuse, mental health, both, general health, other), hotline operation, Opioid Treatment Programs and medication dispensed/prescribed, languages in which treatment is provided, type of treatment provided, number of clients (total and under age 18), number of beds, types of payment accepted, sliding fee scale, special programs offered, facility accreditation and licensure/certification, and managed care agreements.

The National Survey of Substance Abuse Treatment Services (N-SSATS) is designed to collect information from all facilities in the United States, both public and private, that provide substance abuse treatment. N-SSATS provides the mechanism for quantifying the dynamic character and composition of the United States substance abuse treatment delivery system. The objectives of N-SSATS are to collect multipurpose data that can be used to assist the Substance Abuse and Mental Health Services Administration (SAMHSA) and state and local governments in assessing the nature and extent of services provided and in forecasting treatment resource requirements, update SAMHSA's Inventory of Substance Abuse Treatment Services (I-SATS), analyze general treatment services trends, and generate the National Directory of Drug and Alcohol Abuse Treatment Programs and its online equivalent, the Substance Abuse Treatment Facility Locator.

Data are collected on topics including facility operation, services offered (assessment, substance abuse therapy and counseling, pharmacotherapies, testing, transitional, ancillary), primary focus (substance abuse, mental health, both, general health, other), hotline operation, Opioid Treatment Programs and medication dispensed/prescribed, languages in which treatment is provided, type of treatment provided, number of clients (total and under age 18), number of beds, types of payment accepted, sliding fee scale, special programs offered, facility accreditation and licensure/certification, and managed care agreements.

The National Survey of Substance Abuse Treatment Services (N-SSATS) is designed to collect information from all facilities in the United States, both public and private, that provide substance abuse treatment. N-SSATS provides the mechanism for quantifying the dynamic character and composition of the United States substance abuse treatment delivery system. The objectives of N-SSATS are to collect multipurpose data that can be used to assist the Substance Abuse and Mental Health Services Administration (SAMHSA) and state and local governments in assessing the nature and extent of services provided and in forecasting treatment resource requirements, update SAMHSA's Inventory of Substance Abuse Treatment Services (I-SATS), analyze general treatment services trends, and generate the National Directory of Drug and Alcohol Abuse Treatment Programs and its online equivalent, the Substance Abuse Treatment Facility Locator.

Data are collected on topics including facility operation, services offered (assessment, substance abuse therapy and counseling, pharmacotherapies, testing, transitional, ancillary), primary focus (substance abuse, mental health, both, general health, other), hotline operation, Opioid Treatment Programs and medication dispensed, languages in which treatment is provided, type of treatment provided, number of clients (total and under age 18), number of beds, types of payment accepted, sliding fee scale, special programs offered, facility accreditation and licensure/certification, and managed care agreements.

The National Survey of Substance Abuse Treatment Services (N-SSATS) is designed to collect information from all facilities in the United States, both public and private, that provide substance abuse treatment. N-SSATS provides the mechanism for quantifying the dynamic character and composition of the United States substance abuse treatment delivery system. The objectives of N-SSATS are to collect multipurpose data that can be used to assist the Substance Abuse and Mental Health Services Administration (SAMHSA) and state and local governments in assessing the nature and extent of services provided and in forecasting treatment resource requirements, to update SAMHSA's Inventory of Substance Abuse Treatment Services (I-SATS), to analyze general treatment services trends, and to generate the National Directory of Drug and Alcohol Abuse Treatment Programs and its online equivalent, the Substance Abuse Treatment Facility Locator.

Data are collected on topics including facility operation, services offered (assessment and pre-treatment, substance abuse therapy and counseling, pharmacotherapies, testing, transitional, ancillary), primary focus (substance abuse, mental health, both, general health, and other), hotline operation, Opioid Treatment Programs and medication dispensed/prescribed, languages in which treatment is provided, type of treatment provided, number of clients (total and under age 18), number of beds, types of payment accepted, sliding fee scale, special programs offered, facility accreditation and licensure/certification, and managed care agreements.

The National Survey of Substance Abuse Treatment Services (N-SSATS) is designed to collect information from all facilities in the United States, both public and private, that provide substance abuse treatment. N-SSATS provides the mechanism for quantifying the dynamic character and composition of the United States substance abuse treatment delivery system. The objectives of N-SSATS are to collect multipurpose data that can be used to assist the Substance Abuse and Mental Health Services Administration (SAMHSA) and state and local governments in assessing the nature and extent of services provided and in forecasting treatment resource requirements, update SAMHSA's Inventory of Substance Abuse Treatment Services (I-SATS), analyze general treatment services trends, and generate the National Directory of Drug and Alcohol Abuse Treatment Programs and its online equivalent, the Substance Abuse Treatment Facility Locator.

Data are collected on topics including facility operation, services offered (assessment, substance abuse therapy and counseling, pharmacotherapies, testing, transitional, ancillary), primary focus (substance abuse, mental health, both, general health, other), hotline operation, Opioid Treatment Programs and medication dispensed, languages in which treatment is provided, type of treatment provided, number of clients (total and under age 18), number of beds, types of payment accepted, sliding fee scale, special programs offered, facility accreditation and licensure/certification, and managed care agreements.

The National Mental Health Services Survey (N-MHSS) is an annual survey designed to collect statistical information on the numbers and characteristics of all known mental health treatment facilities within the 50 States, the District of Columbia, and the U.S. territories. In every other year, beginning in 2014, the survey also collects statistical information on the numbers and demographic characteristics of persons served in these treatment facilities as of a specified survey reference date.

The N-MHSS is the only source of national and State-level data on the mental health service delivery system reported by both publicly-operated and privately-operated specialty mental health treatment facilities, including: public psychiatric hospitals; private psychiatric hospitals, non-federal general hospitals with separate psychiatric units; U.S. Department of Veterans Affairs medical centers; residential treatment centers for children; residential treatment centers for adults; outpatient or day treatment or partial hospitalization mental health facilities; and multi-setting (non-hospital) mental health facilities.

The N-MHSS complements the information collected through SAMHSA's survey of substance abuse treatment facilities, the National Survey of Substance Abuse Treatment Services (N-SSATS). Treatment facility Information from the N-MHSS is used to populate the mental health component of SAMHSA's online Behavioral Health Treatment Services Locator.

MOUD remains an underutilized evidence-based practice with potential to reduce opioid use disorder (OUD) and save lives. Washington State expanded its Hub & Spoke (H&S) model for OUD medication treatment (MOUD: buprenorphine, methadone, naltrexone) by funding additional networks and developing a low-barrier, Opioid Treatment Network (OTN) model. The Washington H&S model was designed as a flexible approach incorporating primary care and substance use treatment programs, referral organizations, nurse care managers and care navigators. The OTN model offers MOUD induction in non-traditional settings (e.g., emergency departments, jails) with connections to community partners who will offer MOUD maintenance.

This study examined the implementation and effectiveness of the H&S and OTN models for increasing MOUD treatment and improving outcomes for people with OUD. Washington's H&S and OTN interventions were funded through federal STR/SOR opioid response grants, and the expanded H&S networks were funded through the state. The study, Hub and Spoke Opioid Treatment Networks: 2nd Generation Approaches to Improve Medication Treatment for Opioid Use Disorders (R01DA0561067), and its supplement (R01DA0561067S1) was part of NIH's HEAL initiative, and built on an earlier study (R33DA045851). All three studies were supported by the National Institute on Drug Abuse.

Expanding Access to Low-Barrier Opioid Use Disorder Treatment in Non-Traditional Settings: Washington's Opioid Treatment Network

• Increasing utilization of medications that treat opioid use disorders (MOUD) remains an essential strategy to curb the opioid crisis nationwide, especially among rural areas where access can present challenges. Washington State expanded access to MOUD through its opioid treatment networks (OTN), which provide low-barrier access to MOUD in non-traditional settings with an emphasis on buprenorphine and rural locations. The study examined changes in buprenorphine utilization between Medicaid beneficiaries who initiated treatment at OTNs compared to individuals outside OTN facilities and by rural-urban residence.

Differential Changes in Use of Medications for Opioid Use Disorder by Race-Ethnicity: Effects of a Hub-and-Spoke Model

• This study assessed whether delivery of opioid use disorder (OUD) treatment through a hub and spoke (HS) model is associated with better adherence to psychotropic medication treatment, compared to usual treatment. Washington State's HS model required each network to include at least one mental health program, so it was hypothesized that it would improve psychotropic medication adherence for people with both a mental health disorder (MHD) and an OUD.

Treatment for Comorbid Mental Health Disorders Among Patients Treated for Opioid Disorder: The Role of a Hub and Spoke Intervention

• The research team examined, separately for different racial-ethnic groups, whether use of medications for opioid use disorder (MOUD) increased more among people treated in a hub-and-spoke care model than among people treated in a non-hub-and-spoke model.

The Behavioral Risk Factor Surveillance System (BRFSS) is a system of health-related telephone surveys that collect state data about U.S. residents regarding their health-related risk behaviors, chronic health conditions, and use of preventive services. Established in 1984 with 15 states, BRFSS now collects data in all 50 states as well as the District of Columbia and three U.S. territories. BRFSS completes more than 400,000 adult interviews each year.

The MIDUS Refresher study Survey (2011-2014 ICPSR 36532) recruited a national probability sample of 3,577 adults, aged 25 to 74, designed to replenish the original MIDUS 1 baseline cohort and paralleling the five decadal age groups of the MIDUS 1 baseline survey (ICPSR 2760). The MIDUS Refresher survey employed the same comprehensive assessments as those assembled on the core longitudinal MIDUS sample, but with additional questions about impacts of the economic recession of 2008-09. The MIDUS Refresher Biomarker study (2012-2016) obtained data from 863 respondents (n=746 Main sample, n=117 African Americans from Milwaukee) who completed the MIDUS Refresher Survey.

The purpose of the Refresher Biomarker Project (Project 4) parallels that of the MIDUS 2 Biomarker project (ICPSR 29282), which collected comprehensive biological assessments on a subsample of MIDUS respondents, thus facilitating analyses that integrate behavioral and psychosocial factors with biological regulation/dysregulation, broadly defined. The aim was to use such data to explicate biopsychosocial pathways that contributed to diverse health outcomes. A further theme was to examine period effects on health (mental and physical) related to the economic recession by comparing the pre-recession MIDUS sample with the post-recession MIDUS Refresher sample. A further objective of the MIDUS Refresher sample was to strengthen cross-project analyses by increasing the sample sizes available for testing hypotheses regarding the interplay of key factors (e.g., socioeconomic status, gender, psychosocial factors, biological factors) in mid- and later-life health.

Biomarker data collection was carried out at hypothalamic-pituitary-adrenal axis, the autonomic nervous system, the immune system, cardiovascular system, musculoskeletal system, antioxidants, and three General Clinical Research Centers (at UCLA, University of Wisconsin, and Georgetown University). The biomarkers reflect functioning of the metabolic processes. Our specimens (fasting blood draw, 12-hour urine, saliva) allowed for assessment of multiple indicators within these major systems. The protocol also included assessments by clinicians or trained staff, including vital signs, morphology, functional capacities including 3 dimensional gait analysis, bone densitometry, body composition, ankle brachial index, medication usage, and a physical exam. Project staff obtained indicators of heart-rate variability, beat to beat blood pressure, respiration, and salivary cortisol assessments during an experimental protocol that included both a cognitive and orthostatic challenge. Finally, to augment the self-reported data collected in Survey (Project 1), participants completed a medical history, self-administered questionnaire, and self-reported sleep assessments. For respondents at one site (UW-Madison), objective sleep assessments were also obtained with an Actiwatch(R) activity monitor.

The National Survey on Drug Use and Health (NSDUH) series (formerly titled National Household Survey on Drug Abuse) primarily measures the prevalence and correlates of drug use in the United States. Detailed NSDUH 2008 documentation is available from SAMHSA. The surveys are designed to provide quarterly, as well as annual, estimates. Information is provided on the use of illicit drugs, alcohol, and tobacco among members of United States households aged 12 and older. Questions included age at first use as well as lifetime, annual, and past-month usage for the following drug classes: marijuana, cocaine (and crack), hallucinogens, heroin, inhalants, alcohol, tobacco, and nonmedical use of prescription drugs, including pain relievers, tranquilizers, stimulants, and sedatives. The survey covered substance abuse treatment history and perceived need for treatment, and included questions from the Diagnostic and Statistical Manual (DSM) of Mental Disorders that allow diagnostic criteria to be applied. The survey included questions concerning treatment for both substance abuse and mental health related disorders. Respondents were also asked about personal and family income sources and amounts, health care access and coverage, illegal activities and arrest record, problems resulting from the use of drugs, and needle-sharing. Questions introduced in previous administrations were retained in the 2008 survey, including questions asked only of respondents aged 12 to 17. These "youth experiences" items covered a variety of topics, such as neighborhood environment, illegal activities, drug use by friends, social support, extracurricular activities, exposure to substance abuse prevention and education programs, and perceived adult attitudes toward drug use and activities such as school work. Several measures focused on prevention-related themes in this section. Also retained were questions on mental health and access to care, perceived risk of using drugs, perceived availability of drugs, driving and personal behavior, and cigar smoking. Questions on the tobacco brand used most often were introduced with the 1999 survey. For this 2008 survey, Adult mental health questions were added to measure symptoms of psychological distress in the worst period of distress that a person experienced in the past 30 days and suicidal ideation. A split-sample design also was included to administer separate sets of questions to assess impairment due to mental health problems. Background information includes gender, race, age, ethnicity, marital status, educational level, job status, veteran status, and current household composition.