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In 1995-1996, the MacArthur Midlife Research Network carried out a national survey of over 7,000 Americans aged 25 to 74 [ICPSR 2760]. The purpose of the study was to investigate the role of behavioral, psychological, and social factors in understanding age-related differences in physical and mental health. The study was innovative for its broad scientific scope, its diverse samples (which included siblings of the main sample respondents and a national sample of twin pairs), and its creative use of in-depth assessments in key areas (e.g. daily diary of stressful experiences [ICPSR 3725] and cognitive functioning [ICPSR 3596]) on a subset of participants. A detailed description of the study and findings generated by it are available at: http://www.midus.wisc.edu

With support from the National Institute on Aging, a follow-up of the original Midlife Development in the United States (MIDUS) sample was conducted in 2004 (MIDUS 2 [ICPSR 4652]). The daily stress and cognitive functioning projects were repeated and expanded at MIDUS 2; in addition the protocol was expanded to include biomarkers and neuroscience.

In 2013 a third wave (MIDUS 3) of survey data was collected on longitudinal participants. Data collection for this follow-up wave largely repeated baseline assessments (e.g., phone interview and extensive self-administered questionnaire), with additional questions in selected areas such as economic recession experiences. Cognitive functioning data were also collected at the same time, while data collection for the daily diary, biomarker, and neuroscience projects commenced in 2017.

MIDUS also maintains a Colectica portal, which allows users to interact with variables across waves and create customized subsets. Registration is required.

Downloads of Add Health require submission of the following information, which is shared with the original producer of Add Health: supervisor name, supervisor email, and reason for download. A Data Guide for this study is available as a web page and for download.

The National Longitudinal Study of Adolescent to Adult Health (Add Health), 1994-2018 [Public Use] is a longitudinal study of a nationally representative sample of U.S. adolescents in grades 7 through 12 during the 1994-1995 school year. The Add Health cohort was followed into young adulthood with four in-home interviews, the most recent conducted in 2008 when the sample was aged 24-32. Add Health combines longitudinal survey data on respondents' social, economic, psychological, and physical well-being with contextual data on the family, neighborhood, community, school, friendships, peer groups, and romantic relationships.

Add Health Wave I data collection took place between September 1994 and December 1995, and included both an in-school questionnaire and in-home interview. The in-school questionnaire was administered to more than 90,000 students in grades 7 through 12, and gathered information on social and demographic characteristics of adolescent respondents, education and occupation of parents, household structure, expectations for the future, self-esteem, health status, risk behaviors, friendships, and school-year extracurricular activities. All students listed on a sample school's roster were eligible for selection into the core in-home interview sample. In-home interviews included topics such as health status, health-facility utilization, nutrition, peer networks, decision-making processes, family composition and dynamics, educational aspirations and expectations, employment experience, romantic and sexual partnerships, substance use, and criminal activities. A parent, preferably the resident mother, of each adolescent respondent interviewed in Wave I was also asked to complete an interviewer-assisted questionnaire covering topics such as inheritable health conditions, marriages and marriage-like relationships, neighborhood characteristics, involvement in volunteer, civic, and school activities, health-affecting behaviors, education and employment, household income and economic assistance, parent-adolescent communication and interaction, parent's familiarity with the adolescent's friends and friends' parents.

Add Health data collection recommenced for Wave II from April to August 1996, and included almost 15,000 follow-up in-home interviews with adolescents from Wave I. Interview questions were generally similar to Wave I, but also included questions about sun exposure and more detailed nutrition questions. Respondents were asked to report their height and weight during the course of the interview, and were also weighed and measured by the interviewer.

From August 2001 to April 2002, Wave III data were collected through in-home interviews with 15,170 Wave I respondents (now 18 to 26 years old), as well as interviews with their partners. Respondents were administered survey questions designed to obtain information about family, relationships, sexual experiences, childbearing, and educational histories, labor force involvement, civic participation, religion and spirituality, mental health, health insurance, illness, delinquency and violence, gambling, substance abuse, and involvement with the criminal justice system. High School Transcript Release Forms were also collected at Wave III, and these data comprise the Education Data component of the Add Health study.

Wave IV in-home interviews were conducted in 2008 and 2009 when the original Wave I respondents were 24 to 32 years old. Longitudinal survey data were collected on the social, economic, psychological, and health circumstances of respondents, as well as longitudinal geographic data. Survey questions were expanded on educational transitions, economic status and financial resources and strains, sleep patterns and sleep quality, eating habits and nutrition, illnesses and medications, physical activities, emotional content and quality of current or most recent romantic/cohabiting/marriage relationships, and maltreatment during childhood by caregivers. Dates and circumstances of key life events occurring in young adulthood were also recorded, including a complete marriage and cohabitation history, full pregnancy and fertility histories from both men and women, an educational history of dates of degrees and school attendance, contact with the criminal justice system, military service, and various employment events, including the date of first and current jobs, with respective information on occupation, industry, wages, hours, and benefits. Finally, physical measurements and biospecimens were also collected at Wave IV, and included anthropometric measures of weight, height and waist circumference, cardiovascular measures such as systolic blood pressure, diastolic blood pressure, and pulse, metabolic measures from dried blood spots assayed for lipids, glucose, and glycosylated hemoglobin (HbA1c), measures of inflammation and immune function, including High sensitivity C-reactive protein (hsCRP) and Epstein-Barr virus (EBV).

Wave V data collection took place from 2016 to 2018, when the original Wave I respondents were 33 to 43 years old. For the first time, a mixed mode survey design was used. In addition, several experiments were embedded in early phases of the data collection to test response to various treatments. A similar range of data was collected on social, environmental, economic, behavioral, and health circumstances of respondents, with the addition of retrospective child health and socio-economic status questions. Physical measurements and biospecimens were again collected at Wave V, and included most of the same measures as at Wave IV.

The overall goal of Wave VI was to better understand life course trajectories, determinants, and consequences of critical dimensions of aging, health, and health disparities among U.S. early midlife adults. Data collection took place from 2022 to 2025, with participants between the ages of 39 and 51, with an average age of 44. Beyond longitudinal survey measures, newly added questions included those on cumulative stress, discrimination, despair, work-life balance, memory, physical limitations, and caregiving. Continuing from previous waves, home exams collected physical measurements and biospecimens with most of the same measures as Wave V.

The Older Drug Users study was a mixed method, retrospective longitudinal study that interviewed 92 respondents in a large southeastern metropolitan area from January 2009 to August 2010. The goal of the study was to provide in-depth life history on the drug use trajectories of older drug users, specific turning points in drug use patterns, and drug-related health risks over a person's life course.

Quantitiave and qualititative data was collected from each respondent. Two questionnaires were used to collect the quantitative data. The first questionnaire asked about the person's basic demographic information (gender, race, age, and education), health history (has the person been diagnosed with HIV, AIDS, or Hepatitis C), and drug use (route and frequency) and treatment in the past 30 days across ten different substances (tobacco, alcohol, marijuana, hallucinogens/LSD/Ecstasy/club drugs, prescription pills, cocaine, crack, heroin, amphetamines, and methamphetamine).

A second questionnaire was used to serve as a retrospective life history of the person. The questionnaire asked about the same drug use and treatment of the same ten drugs but this time looking at the entire year. Questions were also asked concerning the person's living arrangement, employment, family roles, drug roles, and sexual activity over the course of the year. The questions were repeated for every year of the person's life from birth up to the time the person was interviewed.

The Toledo Adolescent Relationships Study (TARS) explores the relationship qualities and the subjective meanings that motivate adolescent behavior. More specifically, this study seeks to examine the nature and meaning of adolescent relationship experiences (e.g. with family, peers, and dating partners) in an effort to discover how experiences associated with age, gender, race, and ethnicity influence the meaning of dating relationships. The study further investigates the relative impact of dating partners and peers on sexual behavior and contraceptive practices, as well as involvement in other problem behaviors that can contribute independently to sexual risk-taking. The longitudinal design of the Toledo Adolescent Relationships Study (TARS) includes a schedule of follow-up interviews occurring one, three, five, ten, and about eighteen years after the initial interview. Additional waves have since been conducted.

Wave 1 of TARS includes detailed data collected from both parents and adolescent respondents about their relationship experiences, including self-reported data from parents, parent-reported data about adolescent respondents, and self-reported data from adolescent respondents. These data are available as a combined dataset organized by adolescent respondent.

The Toledo Adolescent Relationships Study (TARS) includes several waves of data collection available through ICPSR. Please see the ICPSR Series page for available studies.

The Toledo Adolescent Relationships Study (TARS) explores the relationship qualities and the subjective meanings that motivate adolescent behavior. More specifically, this study seeks to examine the nature and meaning of adolescent relationship experiences (e.g. with family, peers, and dating partners) in an effort to discover how experiences associated with age, gender, race, and ethnicity influence the meaning of dating relationships. The study further investigates the relative impact of dating partners and peers on sexual behavior and contraceptive practices, as well as involvement in other problem behaviors that can contribute independently to sexual risk-taking. The longitudinal design of the Toledo Adolescent Relationships Study (TARS) includes a schedule of follow-up interviews occurring one, three, five, ten, and about eighteen years after the initial interview. Additional waves have since been conducted.

Wave 2 of TARS includes data from follow-up surveys of adolescent respondents conducted approximately one year after the initial TARS survey. These data are accompanied by a series of weights for use in secondary analysis.

The DC Metropolitan Area Drug Study (DC*MADS) was conducted in 1991, and included special analyses of homeless and transient populations and of women delivering live births in the DC hospitals. DC*MADS was undertaken to assess the full extent of the drug problem in one metropolitan area. The study was comprised of 16 separate studies that focused on different sub-groups, many of which are typically not included or are underrepresented in household surveys.

The Homeless and Transient Population study examines the prevalence of illicit drug, alcohol, and tobacco use among members of the homeless and transient population aged 12 and older in the Washington, DC, Metropolitan Statistical Area (DC MSA). The sample frame included respondents from shelters, soup kitchens and food banks, major cluster encampments, and literally homeless people. Data from the questionnaires include history of homelessness, living arrangements and population movement, tobacco, drug, and alcohol use, consequences of use, treatment history, illegal behavior and arrest, emergency room treatment and hospital stays, physical and mental health, pregnancy, insurance, employment and finances, and demographics. Drug specific data include age at first use, route of administration, needle use, withdrawal symptoms, polysubstance use, and perceived risk.

The Youth Development Study (YDS) was initiated as a school-based study of adolescent children and their parents to examine the consequences of formative experiences in adolescence for mental health, value formation, educational achievement, and multiple facets of behavioral adjustment. Particular attention was directed to the impacts of early work experience. Data were also obtained about parent-child and peer relationships and experiences in school. As the study continued, the focus shifted to adult development and attainment and, most recently, mid-life adjustment and health. This comprehensive longitudinal study now encompasses three generations: the initial cohort studied from adolescence to mid-life (G2), their parents (G1), and their adolescent children (G3). Data from three generations in the same families enable study of intergenerational relationships and differences in the experience of adolescence and transition to adulthood across parent and child cohorts. The YDS covers a wide range of topics of interest to sociologists, social psychologists, developmental psychologists, and life course scholars, including the development and impacts of agentic resources, socioeconomic attainment, processes of inter- and intra-generational mobility, objective and subjective work conditions, family relationships, intergenerational relationships, mental and physical health, and well-being.

In-school administration of paper surveys during the first four years of the study was supplemented by mailed surveys. Subsequent data collection took place entirely by mail, with 19 surveys conducted between 1988 and 2011. A final survey was conducted on-line in 2019. Survey data was obtained from the parents (G1) of this cohort during the first and fourth waves of the study (1988 and 1991). Surveys of the children (G3) began in 2009, continued in 2010 and 2011 (by mail) and in 2019-2020 (online).

The Youth Development Study measures a wide range of formative experiences and both psychological and behavioral variables, using survey methodology.

The G1 surveys obtained information about socioeconomic background as well as attitudes toward teenage employment, the parents' own employment as teenagers, their current work experiences, and educational expectations for their children.

The G2 surveys during the high school years included detailed questions about students' work and volunteer experiences, as well as experiences in their family, school, and peer groups, with an emphasis on the ways that working affected other life domains, mental health, and well-being. Shorter surveys containing many of the same topics were administered to students in 1992, 1993, and 1994, and included questions about current family and living arrangements. In 1995, a full survey was administered covering the wide range of topics included in previous surveys as well as information about career plans and life events that had occurred in the past five years. G2 Waves 9 through 19 (1997-2011) included many of the same questions contained in earlier surveys and additional sections that focused on the respondents' educational experiences, family relationships, sources of living expenses, and health and well-being. The most recent G2 survey (2019), administered on-line, included questions about support of aging parents. The YDS is unique in its coverage of both objective and subjective work experiences from adolescence to mid-life.

The topics covered by the G3 surveys are very similar to the G2 variables described above. Variables in each G2 and G3 wave are included in cross-wave codebooks, available at the Data Archive Codebook website.

For an overview of the Youth Development Study, see Mortimer, Jeylan T. (2012) "The Evolution, Contributions, and Prospects of the Youth Development Study: An Investigation in Life Course Social Psychology." Social Psychology Quarterly 75(1, March):5-27.