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Center for Education and Drug Abuse Research (CEDAR): Etiological and Prospective Family Study in Southwestern Pennsylvania, Baseline and Follow-Up Data, 1990-2014 (ICPSR 33444)

Released/updated on: 2021-06-30
Geographic coverage: United States, Pennsylvania
Time period: 1990-01-01--2014-01-01
The Center for Education and Drug Abuse Research (CEDAR) conducted research on 775 families enrolled in the Center's prospective investigations into the etiology of substance use disorder (SUD). The pro-bands are men with lifetime presence/absence of SUD consequent to use of an illicit drug who have a 10-12 year old biological son or daughter. The biological children of SUD men are assigned to the high average risk (HAR) group whereas offspring of men without SUD, having neither axis 1 disorder ("normal") nor SUD psychiatric disorder, are assigned to the low average risk (LAR) group. A second control group (Psych control) was also collected, in whom the fathers had a lifetime DSM-III-R diagnosis of any psychiatric disorder not related to substance use. The sample sizes are as follows: HAR = 344, LAR = 350, and Psych = 81. The children had follow-up evaluations conducted at ages 12-14, 16, 19, and annually thereafter until age 30. CEDAR has already shown that they can predict in 10-12 year old youth cannabis use disorder by age 22 with approximately 70 percent accuracy, thereby substantiating the paradigm, subject recruitment strategy, and measurement protocols. Multidisciplinary research was conducted on family members (father, mother, children) with the objective of elucidating the genetic, bio-behavioral, and environmental factors on development of SUD consequent to use of illegal drugs. Research protocols are organized into three thematically connected research modules (Neurogenetics, Developmental Psychopathology, and Translation) linking etiology and prevention. The research components thus align with the NIH Roadmap model such that basic science informs clinical research leading to prevention guided by an understanding of etiology. In addition to module-level research, faculty also participate in three organizational aims: (1) Devise a practical scale to quantify the transmissible liability to SUD; (2) Empirically test a bio-psychological theory of SUD etiology focusing on off-time maturation leading to psychological dysregulation predisposing to SUD; and, (3) Delineate SUD liability variants within an ontogenetic framework.
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Health and Aging in Africa: A Longitudinal Study of an INDEPTH Community in South Africa [HAALSI]: Agincourt, South Africa, 2015-2022 (ICPSR 36633)

Released/updated on: 2023-03-13
Geographic coverage: Africa, South Africa, Global
Time period: 2014-01-01--2015-01-01, 2018-01-01--2019-01-01, 2021-01-01--2022-01-01

The Health and Aging in Africa: A Longitudinal Study of an INDEPTH Community in South Africa (HAALSI) study is a population-based survey that aims to examine and characterize a population of older men and women in rural South Africa with respect to health, physical and cognitive function, aging, and well-being, in harmonization with other Health and Retirement Studies.

The baseline survey was conducted among 5,059 men and women aged 40 years or older, who were sampled from within the existing framework of the Agincourt health and socio-demographic surveillance system (AHDSS), in rural Mpumalanga province, South Africa. Survey data were collected on cognitive and physical functioning, social networks, cardiometabolic disease and risk factors, HIV and HIV risk, and economic well-being. The survey also included anthropometric measures and point-of-care blood tests for hemoglobin, glucose and lipids. Dried bloodspots (DBS) were collected at the survey and later tested for HIV, HIV viral load, glucose and CRP. A sub-sample had more extensive laboratory follow-up testing, which will be available in future data releases. A second wave of the survey was administered in 2018 through 2019, and a third wave of the survey was administered in 2021 through 2022.

Demographic information includes age, sex, income, education, marital status, number of children, and employment.

Harvard dataverse hosts an additional restricted-use dataset which compliments this collection, the HAALSI Baseline HIV Biomarker Data; users interested in obtaining these data must request access based on the terms outlined in the data use agreement.

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NICHD Study of Early Child Care and Youth Development: Phase I, 1991-1994 [United States] (ICPSR 21940)

Released/updated on: 2018-06-25
Geographic coverage: North Carolina, United States, Massachusetts, California, Kansas, Virginia, Arkansas, Wisconsin, Washington, Pennsylvania
Time period: 1991-01-01--1994-01-01

The overall purpose of this study was to examine the influence of variations in early childcare histories on the psychological development of infants and toddlers from a variety of family backgrounds. This general objective was addressed through a prospective, longitudinal study of the experiences of 1,364 children and their families, which took into account the complex interactions among child characteristics and those of the human and physical environments in which the children were reared.

Research Goals

The specific research aims were as follows:

  • Examining the relationship between infants' childcare arrangements (defined in terms of hours, type, quality, and stability of care and the age at which the child entered care) and children's concurrent and long-term development. Specifically, the study investigated the association between children's experiences in childcare and their social, emotional, language, and cognitive development. The social-emotional assessments included measures of attachment, independence, compliance, behavior problems, prosocial and antisocial behavior, and general competence in interacting with peers. Cognitive variables include general developmental level and problem solving skills. Language assessments incorporated measures of children's expressive and receptive communicative competence.

  • Examining whether the social ecology of the home moderates the effects of childcare, i.e., whether children from different home environments are differentially affected by similar childcare experiences. The study examined the moderating effects of parents' values and attitudes, psychological adjustment and mental health, stress and social support, child-rearing practices, time use, interactions with the child, the marital relationship, and family demographics.

  • Examining whether individual differences among children moderate the effects of infant care on child development. The study examined the moderating effects of such child characteristics as age, sex, health, birth order, and temperament.

  • Identify demographic and family characteristics associated with families' childcare decisions. The study examined whether specific childcare arrangements are related to the parents' social class, marital status, psychological adjustment and personality, child-rearing values and attitudes, parenting practices, stress, social support, marital relationship, and the availability of childcare in the community.

  • Provide a natural history of infant care in the 1990s, and help establish a baseline of data pertaining to the kinds of care being used by families. Whereas other national databases, such as those provided by the United States Census Bureau, provide static estimates of the number of children in different types of childcare, this network study supplements that knowledge with longitudinal data on successive enrollments into day care at various ages, patterns of arrangements used concurrently and over time, and the stability of arrangements during the first three years of life. One of the most valuable aspects of the collaborative study is the opportunity it provides to obtain a more complete and accurate picture of patterns of infant care used by families today. Census surveys use only gross categories of care (e.g., center vs. in-home). In this study, more fine-grained information regarding the types of centers and home-care facilities was gathered.

  • Examine the consequences for families of maternal employment and childcare choices. Family relationships, parental mental health, family stress, and so on, are not just inputs to child development or moderators of childcare effects, they are also outcomes. High-quality childcare may alleviate family stress and enhance parental adjustment. Low-quality childcare may add to the stress parents experience. Although the main focus in the study was on the effect of childcare on the child, the study also examined the effect of childcare on the family.

  • Identify demographic characteristics of childcare associated with childcare quality. Of interest to policy makers is another aspect of the study, the investigation of those regulatory characteristics that predict care of higher quality. These characteristics included the level and type of caregiver training, the size of the childcare group, the auspices of the childcare program (public/private, profit/nonprofit, independent/chain, employer-sponsored/church-based), whether the facility was licensed or unlicensed, the level of payment and fees, and whether the caregiver was a relative of the family.

Data File Organization

309 data files were compiled for this study and are organized into 3 main groups:

  1. Analytical Data Sets (ADS) -- The raw data were examined and composites defined by small groups of individual principal investigators according to the demographic, family, childcare, and child outcome content of the data. The psychometric and distributional qualities of the variables, along with site differences, were examined. A set of variables that were psychometrically and distributionally acceptable to be used in analytic analyses was designed to test the study hypotheses. These data files comprise Parts 1-42 of the study data material.

  2. Supplemental Data Sets -- New and revised analysis variables as well as across-time mean scores and primary composites were produced as a supplement to the original Analytical Datasets. These data files comprise Parts 43-55 of the study data material.

  3. Raw Data Sets -- The raw data were made available and comprise Parts 56-309 of the study data material.

Training Workshop

A three-day summer training workshop on the SECCYD was put on by NICHD at the Inter-University Consortium for Political and Social Research in Ann Arbor, Michigan in 2010. The binder from that workshop, which includes the Powerpoint slides used during presentations, are freely available to the public as part of the study documentation.

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NICHD Study of Early Child Care and Youth Development: Phase II, 1995-1999 [United States] (ICPSR 21941)

Released/updated on: 2018-06-25
Geographic coverage: North Carolina, United States, Massachusetts, California, Kansas, Virginia, Arkansas, Wisconsin, Washington, Pennsylvania
Time period: 1995-01-01--1999-01-01

The overall purpose of this study was to examine the influence of variations in early childcare histories on the psychological development of infants and toddlers from a variety of family backgrounds. This general objective was addressed through a prospective, longitudinal study of the experiences of 1,364 children and their families, which took into account the complex interactions among child characteristics and those of the human and physical environments in which the children were reared.

Research Goals

The specific research aims were as follows:

  • Examining the relationship between infants' childcare arrangements (defined in terms of hours, type, quality, and stability of care and the age at which the child entered care) and children's concurrent and long-term development. Specifically, the study investigated the association between children's experiences in childcare and their social, emotional, language, and cognitive development. The social-emotional assessments included measures of attachment, independence, compliance, behavior problems, prosocial and antisocial behavior, and general competence in interacting with peers. Cognitive variables include general developmental level and problem solving skills. Language assessments incorporated measures of children's expressive and receptive communicative competence.

  • Examining whether the social ecology of the home moderates the effects of childcare, i.e., whether children from different home environments are differentially affected by similar childcare experiences. The study examined the moderating effects of parents' values and attitudes, psychological adjustment and mental health, stress and social support, child-rearing practices, time use, interactions with the child, the marital relationship, and family demographics.

  • Examining whether individual differences among children moderate the effects of infant care on child development. The study examined the moderating effects of such child characteristics as age, sex, health, birth order, and temperament.

  • Identify demographic and family characteristics associated with families' childcare decisions. The study examined whether specific childcare arrangements are related to the parents' social class, marital status, psychological adjustment and personality, child-rearing values and attitudes, parenting practices, stress, social support, marital relationship, and the availability of childcare in the community.

  • Provide a natural history of infant care in the 1990s, and help establish a baseline of data pertaining to the kinds of care being used by families. Whereas other national databases, such as those provided by the United States Census Bureau, provide static estimates of the number of children in different types of childcare, this network study supplements that knowledge with longitudinal data on successive enrollments into day care at various ages, patterns of arrangements used concurrently and over time, and the stability of arrangements during the first three years of life. One of the most valuable aspects of the collaborative study is the opportunity it provides to obtain a more complete and accurate picture of patterns of infant care used by families today. Census surveys use only gross categories of care (e.g., center vs. in-home). In this study, more fine-grained information regarding the types of centers and home-care facilities was gathered.

  • Examine the consequences for families of maternal employment and childcare choices. Family relationships, parental mental health, family stress, and so on, are not just inputs to child development or moderators of childcare effects, they are also outcomes. High-quality childcare may alleviate family stress and enhance parental adjustment. Low-quality childcare may add to the stress parents experience. Although the main focus in the study was on the effect of childcare on the child, the study also examined the effect of childcare on the family.

  • Identify demographic characteristics of childcare associated with childcare quality. Of interest to policy makers is another aspect of the study, the investigation of those regulatory characteristics that predict care of higher quality. These characteristics included the level and type of caregiver training, the size of the childcare group, the auspices of the childcare program (public/private, profit/nonprofit, independent/chain, employer-sponsored/church-based), whether the facility was licensed or unlicensed, the level of payment and fees, and whether the caregiver was a relative of the family.

Data File Organization

193 data files were compiled for this study and are organized into 3 main groups:

  1. Analytical Data Sets (ADS) -- The raw data were examined and composites defined by small groups of individual principal investigators according to the demographic, family, childcare, and child outcome content of the data. The psychometric and distributional qualities of the variables along with site differences were examined. A set of variables that was psychometrically and distributionally acceptable to be used in analytic analyses was designed to test the study hypotheses. These data files comprise Parts 1-24 of the study data material.

  2. Supplemental Data Sets -- New and revised analysis variables as well as across-time mean scores and primary composites were produced as a supplement to the original Analytical Data Sets. These data files comprise Parts 25-27 of the study data material.

  3. Raw Data Sets -- The raw data were made available and comprise Parts 28-193 of the study data material.

Training Workshop

A three-day summer training workshop on the SECCYD was put on by NICHD at the Inter-University Consortium for Political and Social Research in Ann Arbor, Michigan in 2010. The binder from that workshop, which includes the Powerpoint slides used during presentations, are freely available to the public as part of the study documentation.

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NICHD Study of Early Child Care and Youth Development: Phase III, 2000-2004 [United States] (ICPSR 21942)

Released/updated on: 2018-06-25
Geographic coverage: North Carolina, United States, Massachusetts, California, Kansas, Virginia, Arkansas, Wisconsin, Washington, Pennsylvania
Time period: 2000-01-01--2004-01-01

The overall purpose of this study was to examine the influence of variations in early childcare histories on the psychological development of infants and toddlers from a variety of family backgrounds. This general objective was addressed through a prospective, longitudinal study of the experiences of 1,364 children and their families, which took into account the complex interactions among child characteristics and those of the human and physical environments in which the children were reared.

Research Goals

The specific research aims were as follows:

  • Examining the relationship between infants' childcare arrangements (defined in terms of hours, type, quality, and stability of care and the age at which the child entered care) and children's concurrent and long-term development. Specifically, the study investigated the association between children's experiences in childcare and their social, emotional, language, and cognitive development. The social-emotional assessments included measures of attachment, independence, compliance, behavior problems, prosocial and antisocial behavior, and general competence in interacting with peers. Cognitive variables include general developmental level and problem solving skills. Language assessments incorporated measures of children's expressive and receptive communicative competence.

  • Examining whether the social ecology of the home moderates the effects of childcare, i.e., whether children from different home environments are differentially affected by similar childcare experiences. The study examined the moderating effects of parents' values and attitudes, psychological adjustment and mental health, stress and social support, child-rearing practices, time use, interactions with the child, the marital relationship, and family demographics.

  • Examining whether individual differences among children moderate the effects of infant care on child development. The study examined the moderating effects of such child characteristics as age, sex, health, birth order, and temperament.

  • Identify demographic and family characteristics associated with families' childcare decisions. The study examined whether specific childcare arrangements are related to the parents' social class, marital status, psychological adjustment and personality, child-rearing values and attitudes, parenting practices, stress, social support, marital relationship, and the availability of childcare in the community.

  • Provide a natural history of infant care in the 1990s, and help establish a baseline of data pertaining to the kinds of care being used by families. Whereas other national databases, such as those provided by the United States Census Bureau, provide static estimates of the number of children in different types of childcare, this network study supplements that knowledge with longitudinal data on successive enrollments into day care at various ages, patterns of arrangements used concurrently and over time, and the stability of arrangements during the first three years of life. One of the most valuable aspects of the collaborative study is the opportunity it provides to obtain a more complete and accurate picture of patterns of infant care used by families today. Census surveys use only gross categories of care (e.g., center vs. in-home). In this study, more fine-grained information regarding the types of centers and home-care facilities was gathered.

  • Examine the consequences for families of maternal employment and childcare choices. Family relationships, parental mental health, family stress, and so on, are not just inputs to child development or moderators of childcare effects, they are also outcomes. High-quality childcare may alleviate family stress and enhance parental adjustment. Low-quality childcare may add to the stress parents experience. Although the main focus in the study was on the effect of childcare on the child, the study also examined the effect of childcare on the family.

  • Identify demographic characteristics of childcare associated with childcare quality. Of interest to policy makers is another aspect of the study, the investigation of those regulatory characteristics that predict care of higher quality. These characteristics included the level and type of caregiver training, the size of the childcare group, the auspices of the childcare program (public/private, profit/nonprofit, independent/chain, employer-sponsored/church-based), whether the facility was licensed or unlicensed, the level of payment and fees, and whether the caregiver was a relative of the family.

Data File Organization

504 data files were compiled for this study and are organized into 4 main groups:

  1. Analytical Data Sets (ADS) -- The raw data were examined and composites defined by small groups of individual principal investigators according to the demographic, family, childcare, and child outcome content of the data. The psychometric and distributional qualities of the variables along with site differences were examined. A set of variables that was psychometrically and distributionally acceptable to be used in analytic analyses was designed to test the study hypotheses. These data files comprise Parts 1-49 of the study data material.

  2. Supplemental Data Sets -- New and revised analysis variables as well as across-time mean scores and primary composites were produced as a supplement to the original Analytical Data Sets. These data files comprise Parts 50-55 of the study data material.

  3. Raw Census-Related Data Sets -- Files were produced using geocoded addresses for survey respondents to match block group level data from the 1990 and 2000 Censuses for investigators to create additional measures of interest from the geocoded addresses. These data files comprise Parts 56-58 of the study data material.

  4. Raw Data Sets -- The raw data were made available and comprise Parts 59-505 of the study data material.

Training Workshop

A three-day summer training workshop on the SECCYD was put on by NICHD at the Inter-University Consortium for Political and Social Research in Ann Arbor, Michigan in 2010. The binder from that workshop, which includes the Powerpoint slides used during presentations, are freely available to the public as part of the study documentation.

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NICHD Study of Early Child Care and Youth Development: Phase IV, 2005-2007 [United States] (ICPSR 22361)

Released/updated on: 2018-06-25
Geographic coverage: North Carolina, United States, Massachusetts, California, Kansas, Virginia, Arkansas, Wisconsin, Washington, Pennsylvania
Time period: 2005-01-01--2007-01-01

The overall purpose of this study was to examine the influence of variations in early childcare histories on the psychological development of infants and toddlers from a variety of family backgrounds. This general objective was addressed through a prospective, longitudinal study of the experiences of 1,364 children and their families, which took into account the complex interactions among child characteristics and those of the human and physical environments in which the children were reared.

Research Goals

The specific research aims were as follows:

  • Examining the relationship between infants' childcare arrangements (defined in terms of hours, type, quality, and stability of care and the age at which the child entered care) and children's concurrent and long-term development. Specifically, the study investigated the association between children's experiences in childcare and their social, emotional, language, and cognitive development. The social-emotional assessments included measures of attachment, independence, compliance, behavior problems, prosocial and antisocial behavior, and general competence in interacting with peers. Cognitive variables include general developmental level and problem solving skills. Language assessments incorporated measures of children's expressive and receptive communicative competence.

  • Examining whether the social ecology of the home moderates the effects of childcare, i.e., whether children from different home environments are differentially affected by similar childcare experiences. The study examined the moderating effects of parents' values and attitudes, psychological adjustment and mental health, stress and social support, child-rearing practices, time use, interactions with the child, the marital relationship, and family demographics.

  • Examining whether individual differences among children moderate the effects of infant care on child development. The study examined the moderating effects of such child characteristics as age, sex, health, birth order, and temperament.

  • Identify demographic and family characteristics associated with families' childcare decisions. The study examined whether specific childcare arrangements are related to the parents' social class, marital status, psychological adjustment and personality, child-rearing values and attitudes, parenting practices, stress, social support, marital relationship, and the availability of childcare in the community.

  • Provide a natural history of infant care in the 1990s, and help establish a baseline of data pertaining to the kinds of care being used by families. Whereas other national databases, such as those provided by the United States Census Bureau, provide static estimates of the number of children in different types of childcare, this network study supplements that knowledge with longitudinal data on successive enrollments into day care at various ages, patterns of arrangements used concurrently and over time, and the stability of arrangements during the first three years of life. One of the most valuable aspects of the collaborative study is the opportunity it provides to obtain a more complete and accurate picture of patterns of infant care used by families today. Census surveys use only gross categories of care (e.g., center vs. in-home). In this study, more fine-grained information regarding the types of centers and home-care facilities was gathered.

  • Examine the consequences for families of maternal employment and childcare choices. Family relationships, parental mental health, family stress, and so on, are not just inputs to child development or moderators of childcare effects, they are also outcomes. High-quality childcare may alleviate family stress and enhance parental adjustment. Low-quality childcare may add to the stress parents experience. Although the main focus in the study was on the effect of childcare on the child, the study also examined the effect of childcare on the family.

  • Identify demographic characteristics of childcare associated with childcare quality. Of interest to policy makers is another aspect of the study, the investigation of those regulatory characteristics that predict care of higher quality. These characteristics included the level and type of caregiver training, the size of the childcare group, the auspices of the childcare program (public/private, profit/nonprofit, independent/chain, employer-sponsored/church-based), whether the facility was licensed or unlicensed, the level of payment and fees, and whether the caregiver was a relative of the family.

Data File Organization

158 data files were compiled for this study and are organized into 4 main groups:

  1. Analytical Data Sets (ADS)-- The raw data were examined and composites defined by small groups of individual principal investigators according to the demographic, family, childcare, and child outcome content of the data. The psychometric and distributional qualities of the variables along with site differences were examined. A set of variables that was psychometrically and distributionally acceptable to be used in analytic analyses was designed to test the study hypotheses. These data files comprise Parts 1-19 of the study data material.

  2. Supplemental Data Sets -- New and revised analysis variables as well as across-time mean scores and primary composites were produced as supplements to the original Analytical Data Sets. These data files are Parts 20-26 of the study data material.

  3. Raw Census-Related Data Sets -- Files were produced using geocoded addresses for survey respondents to match block group-level data from the 1990 and 2000 Censuses for investigators to create additional measures of interest from the geocoded addresses. These data files comprise Parts 27-30 of the study data material.

  4. Raw Data Sets -- The raw data were made available and comprise Parts 31-158 of the study data material.

Included in this phase of the study are the output of several third-party software programs that were used during Phases II, III and IV to collect data for specific tasks or activities. These programs produced one output data file per subject, which were combined to produce some of the raw data files for those studies. The original program output is included as expanded documentation in this phase of the study.

Training Workshop

A three-day summer training workshop on the SECCYD was put on by NICHD at the Inter-University Consortium for Political and Social Research in Ann Arbor, Michigan in 2010. The binder from that workshop, which includes the Powerpoint slides used during presentations, are freely available to the public as part of the study documentation.

Curated
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Perception and Memory Experiments Using Drug Names [2010, Canada] (ICPSR 34122)

Released/updated on: 2013-04-30
Geographic coverage: Canada, Ontario, Global
Time period: 2012-03-28--2012-03-29, 2012-07-05--2012-07-06
Drug names that look and sound alike are a leading cause of medication errors (e.g., diazepam and diltiazem, hydroxyzine and hydralazine, Paxil and Taxol, fomepizole and omeprazole, Foradil and Toradol). Observational studies of dispensing in outpatient pharmacies suggest that the rate of wrong drug errors -- the type most likely to be the result of name confusion -- is roughly 0.13 percent. With 3.9 billion prescriptions dispensed in 2009, that translates to 5 million wrong drug errors per year in the United States. The purpose of this overall project was to develop, demonstrate, and disseminate a standard protocol for pre-approval testing of drug names, including a standard battery of psycholinguistic tests and data analytic methods, all with comparison to control names and to refine and demonstrate analytic methods by conducting a series of visual perception, auditory perception, and short term memory experiments using drug names as stimuli. The achievement of this aim will provide both regulators and pharmaceutical manufacturers with a scientifically validated, step-by-step method for testing new drug names for confusability. The data for this collection come from four experiments. In each experiment, participants are tested on their ability to correctly identify drug names under four conditions (see study design). Variables include participant reaction time to identify drug names and the percent participants correctly or incorrectly identified drug names. Study participants include medical doctors, nurse practitioners, pharmacists, and pharmacy technicians. Other variables include participant gender, education degree held, primary language spoken, and employment location.