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The Adolescent Substance Abuse Prevention Study (ASAPS) was a randomized field trial designed to test the effectiveness of a new school-based substance abuse prevention program called Take Charge of Your Life (TCYL). The program consisted of two curricula, one for middle schools and the other for high schools, which were delivered through the Drug Abuse Resistance Education network of law enforcement officers (D.A.R.E.). TCYL was developed building on existing D.A.R.E. seventh/eighth grade and tenth/eleventh grade curricula and applied principles and strategies suggested by published literature on effective drug abuse prevention programming and effective middle and high school curricula design. ASAPS was conducted among a 2001-2002 multi-site cohort of seventh graders who were followed for five years until the 2005-2006 school year when they were in the eleventh grade. The first TCYL curriculum was delivered in the treatment schools when the students were in seventh grade and the second was delivered when they were in the ninth grade.

Over the five-year study period, the treatment and control students responded to seven self-administered surveys: (1) at baseline in the seventh grade, (2) post-intervention in the seventh grade, (3) in the eighth grade, (4) pre-intervention in the ninth grade, (5) post-intervention in the ninth grade, (6) in the tenth grade, and (7) in the eleventh grade. Topics covered by the surveys include normative beliefs, social skills, attitudes toward drug use, and self-reported use of alcohol, tobacco, marijuana, and other illicit drugs. The ASAPS data also include measures of implementation fidelity of the seventh and ninth grade TCYL curricula, which were obtained from trained observers who rated the D.A.R.E. officers' delivery in the classroom. The fidelity measures encompass content coverage and instructional strategy.

This data collection comprises two data files, both with public- and restricted-use versions. The first (the Main Data File) contains the students' survey responses and the seventh grade curriculum fidelity measures, while the second (the 9th Grade Officer Observations Data) contains the ninth grade curriculum fidelity measures.

The Community Vulnerability and Responses to Drug-User-Related HIV/AIDS, 1990-2013 [96 Metropolitan Statistical Areas, United States] study (CVAR) was a research study of why large United States Metropolitan Statistical Areas (MSAs) vary over time in their vulnerability to HIV/AIDS among drug users and in MSA responses to HIV/AIDS. This collection contains estimates of HIV prevalence among people who injected drugs (PWID) and among sub-populations of PWID. This collection is comprised of ten datasets with differing amounts of variables and provides trend data that describe the following:

• Epidemiologic outcomes including population prevalence of PWIDs and Non-injecting drug users (NIDUs), and particularly their prevalence among youth; and, among PWIDs, HIV prevalence, late-diagnosis HIV cases, and AIDS incidence and mortality.
• Implementation of evidence-based drug-related interventions including drug abuse treatment, syringe exchange, HIV counseling and testing.
• Implementation of non-evidence-based drug-related interventions including incarceration and arrests of drug users.

The collection contains data on the MSA sub-populations including Black, Hispanic, White and "other" race categories. In addition, some statistics are presented in age range categories such as ages 15-29, 30-64 and 15-64.

The Epidemiologic Catchment Area (ECA) program of research was initiated in response to the 1977 report of the President's Commission on Mental Health. The purpose was to collect data on the prevalence and incidence of mental disorders and on the use of and need for services by the mentally ill. Independent research teams at five universities (Yale University, Johns Hopkins University, Washington University, Duke University, and University of California at Los Angeles), in collaboration with the National Institute for Mental Health, conducted the studies with a core of common questions and sample characteristics. The sites were areas that had previously been designated as Community Mental Health Center catchment areas: New Haven, Connecticut, Baltimore, Maryland, St. Louis, Missouri, Durham, North Carolina, and Los Angeles, California. Each site sampled over 3,000 community residents and 500 residents of institutions, yielding 20,861 respondents overall. The longitudinal ECA design incorporated two waves of personal interviews administered one year apart and a brief telephone interview in between (for the household sample). The diagnostic interview used in the ECA was the NIMH Diagnostic Interview Schedule (DIS), Version III (with the exception of the Yale Wave I survey, which used Version II). Diagnoses were categorized according to the DIAGNOSTIC AND STATISTICAL MANUAL OF MENTAL DISORDERS, 3rd Edition (DSM-III). Diagnoses derived from the DIS include manic episode, dysthymia, bipolar disorder, single episode major depression, recurrent major depression, atypical bipolar disorder, alcohol abuse or dependence, drug abuse or dependence, schizophrenia, schizophreniform, obsessive compulsive disorder, phobia, somatization, panic, antisocial personality, and anorexia nervosa. The DIS uses the Mini-Mental State Examination (MMSE), which measures cognitive functioning, as an indirect measure of the DSM-III Organic Mental Disorders. In the ECA survey, this diagnosis is called cognitive impairment.

This collection features data from 17,327 participants across 2,005 variables. Data from the Los Angeles, California, Catchment (UCLA) are not included. Baseline data (Wave 1) and Wave 2 data were linked to the National Death Index through 2007, which includes primary and contributing causes of death, International Classification of Disease (ICD) codes, and nature of injury variables.