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Midlife in the United States (MIDUS Refresher 1): Biomarker Project, 2012-2016 (ICPSR 36901)

Released/updated on: 2019-11-18

Geographic coverage: United States

Time period: 2012-10-01--2016-08-31

The MIDUS Refresher study Survey (2011-2014 ICPSR 36532) recruited a national probability sample of 3,577 adults, aged 25 to 74, designed to replenish the original MIDUS 1 baseline cohort and paralleling the five decadal age groups of the MIDUS 1 baseline survey (ICPSR 2760). The MIDUS Refresher survey employed the same comprehensive assessments as those assembled on the core longitudinal MIDUS sample, but with additional questions about impacts of the economic recession of 2008-09. The MIDUS Refresher Biomarker study (2012-2016) obtained data from 863 respondents (n=746 Main sample, n=117 African Americans from Milwaukee) who completed the MIDUS Refresher Survey.

The purpose of the Refresher Biomarker Project (Project 4) parallels that of the MIDUS 2 Biomarker project (ICPSR 29282), which collected comprehensive biological assessments on a subsample of MIDUS respondents, thus facilitating analyses that integrate behavioral and psychosocial factors with biological regulation/dysregulation, broadly defined. The aim was to use such data to explicate biopsychosocial pathways that contributed to diverse health outcomes. A further theme was to examine period effects on health (mental and physical) related to the economic recession by comparing the pre-recession MIDUS sample with the post-recession MIDUS Refresher sample. A further objective of the MIDUS Refresher sample was to strengthen cross-project analyses by increasing the sample sizes available for testing hypotheses regarding the interplay of key factors (e.g., socioeconomic status, gender, psychosocial factors, biological factors) in mid- and later-life health.

Biomarker data collection was carried out at hypothalamic-pituitary-adrenal axis, the autonomic nervous system, the immune system, cardiovascular system, musculoskeletal system, antioxidants, and three General Clinical Research Centers (at UCLA, University of Wisconsin, and Georgetown University). The biomarkers reflect functioning of the metabolic processes. Our specimens (fasting blood draw, 12-hour urine, saliva) allowed for assessment of multiple indicators within these major systems. The protocol also included assessments by clinicians or trained staff, including vital signs, morphology, functional capacities including 3 dimensional gait analysis, bone densitometry, body composition, ankle brachial index, medication usage, and a physical exam. Project staff obtained indicators of heart-rate variability, beat to beat blood pressure, respiration, and salivary cortisol assessments during an experimental protocol that included both a cognitive and orthostatic challenge. Finally, to augment the self-reported data collected in Survey (Project 1), participants completed a medical history, self-administered questionnaire, and self-reported sleep assessments. For respondents at one site (UW-Madison), objective sleep assessments were also obtained with an Actiwatch(R) activity monitor.

Curated

National Health Examination Survey, Cycle I, 1959-1962: Demographic Data and Symptoms of Psychological Distress (ICPSR 9209)

Released/updated on: 1992-02-17

Geographic coverage: United States

Time period: 1959-10-01--1962-12-31

The National Health Examination Surveys, Cycle I (NHES I), conducted during the period 1959-1962, were designed to secure statistics on the health status of the population of the United States. More specifically, their purpose was to determine the prevalence of certain chronic diseases, the status of dental health, and the distributions of auditory and visual acuity and certain anthropometric measurements. This collection contains demographic, household, and personal information for each sample person including age, race, sex, income, region, size of residence, usual activity, and sampling weight. Also included are responses to 12 items from a medical history questionnaire that were selected as indicators of psychological distress. The items include past experiences with such symptoms as faintness, sleeping problems, and sweaty hands.

Curated

United States National Health Measurement Study, 2005-2006 (ICPSR 23263)

Released/updated on: 2009-06-23

Geographic coverage: United States

Time period: 2005-06-01--2006-08-31

The National Health Measurement Study (NHMS) surveyed older United States adults with a suite of health-related quality of life (HRQoL) indices to allow comparison and cross-calibration of these instruments. The design oversampled African Americans and older individuals to allow subgroup analyses. Several preference-weighted indices measuring self-reported generic HRQoL are used widely in population surveys and clinical studies in the United States and around the world. These indices are used to evaluate individual and population health. Because they have been developed using econometric methods to elicit utility weights for their scoring systems, they are generally accepted for use in cost-effectiveness analyses of health interventions. Each index uses a multidimensional representation of health, but each index covers the dimensions of health (e.g., physical function, mental function, social function, pain, other symptoms, etc.) differently, and uses questionnaires with different psychometric properties. Each index is scored so that perfect health is represented as 1.0 and dead is represented as 0.0, but they are known to have different scaling properties. Rarely have two or more of these instruments been included in a population survey, so there have been few opportunities to directly compare how they describe and measure health using multi-instrument data. In this study, respondents indicated whether they had been diagnosed with coronary heart disease, stroke, diabetes, arthritis, eye disease, sleep disorder, chronic respiratory disease, clinical depression or anxiety disorder, gastrointestinal ulcer, thyroid disorder, and/or severe chronic back pain. Census tract is not identified, however race composition, education levels, economic factors, and urbanicity of each respondent's census tract of residence are included as contextual variables. Demographic, socioeconomic, and additional health data were elicited. Respondents are characterized by census region of residence, age, gender, marital status, race, ethnicity, education, household income and assets, health insurance, weight, height, smoking status, psychological well-being scales, and everyday and lifetime discrimination items. The data were de-identified, and extensive documentation was developed. The NHMS collected data on 3,844 adults in the continental United States (1,641 males and 2,203 females, 1,086 African Americans).