Post Coital DNA Recovery in Minority Proxy Couples, United States, 2014-2018 (ICPSR 37250)
Version Date: Dec 17, 2019 View help for published
Principal Investigator(s): View help for Principal Investigator(s)
Patricia M. Speck, University of Alabama in Birmingham
Summary View help for Summary
Introduction and Background. Minorities are less likely to report rapes. The Post Coital DNA Recovery (PCDR) study (2009-14) subjects were white (93%) where expanded collection times were not generalizable to minority populations. Evidence reports health and medical differences between races necessitating duplication of previous research in minority populations.
Aims. (1) What is the time period in which it is possible to collect post-coital DNA in minority women using Y-STR laboratory methods? and (2) when compared to the former study sample of minority and non-minority, what are the physiological conditions, factors, or activities in minority couples that influence post-coital DNA recovery?
Design. The design includes mixed methods duplication perfected in the first study, embracing descriptive and inferential techniques. Qualitative research used semi-structured interviews. Aim 1 analysis used PCDR-M data only. Aim 2 combined data from both PCDR and PCDR-M studies. Combined, DNA recovery, a binary outcome accounting for repeated methods in population regression analysis, used Generalized Estimating Equation (GEE) methods.
Fidelity. The strict criteria for adherence included considerable outreach and support of study personnel. PCDR and PCDR-M data combined and compared the two samples, which had specific homogeneity, including same inclusion and elimination criteria in both studies; fidelity to the validated protocol; laboratory method and interpretation for inclusion; duplicate statistical analysis; and interpretation of data. Any variation in key variables met elimination criteria.
Assumptions and Limitations. Assumptions included (1) motivation is altruistic; (2) motivation is incentives and coercion for some; (3) negotiating coitus is difficult and stressful; and (4) similar fidelity and dropout rates. The limitations included (1) a lack of representation for the diverse experiences of rape victims; (2) sample size; (3) self-selection bias; (4) protocol adherence; and (4) advances in laboratory science and DNA kits.
Demographics. Demographic variables included gender, race, and age. Major categories in the dataset included participants' reproductive history, data on female participants' reproductive organs, and childhood abuse.
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Geographic Coverage View help for Geographic Coverage
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Restrictions View help for Restrictions
Access to these data is restricted. Users interested in obtaining these data must complete a Restricted Data Use Agreement, specify the reason for the request, and obtain IRB approval or notice of exemption for their research.Hide
Time Period(s) View help for Time Period(s)
Date of Collection View help for Date of Collection
Data Collection Notes View help for Data Collection Notes
- This collection is related to the Longitudinal Post-Coital DNA Recovery 2010-2014 [UNITED STATES], ICPSR 35254. For similar study information and characteristics, please refer to both studies.
Study Purpose View help for Study Purpose
Aims. (1) What is the time period in which it is possible to collect post-coital DNA in minority women using Y-STR laboratory methods? and (2) when compared to the former study sample of minority and non-minority, what are the physiological conditions, factors, or activities in minority couples that influence post-coital DNA recovery.
Study Design View help for Study Design
The design includes mixed methods duplication perfected in the first study, embracing descriptive and inferential techniques. Qualitative research used semi-structured interviews. Aim 1 analysis used PCDR-M data only. Aim 2 combined data from both PCDR and PCDR-M studies. Combined, DNA recovery, a binary outcome accounting for repeated methods in population regression analysis, used Generalized Estimating Equation (GEE) methods.
Sample View help for Sample
A local recruitment of minority proxy couples occurred through organizational networks and media. Volunteer proxy couples called the study phone to express interest, and the caller was screened for eligibility. Recruitment and screening questions eliminated those with full hysterectomy (must have a cervix), male vasectomy or infertility (must have sperm DNA) and obesity (which lowers sperm count). If not self-eliminated, interested couples and collectors contacted the Principle Investigator (PI) or co-investigator where a telephone discussion about the study and protocol for IRB approved informed consent occurred. Participants received consent paperwork through the U S Post Office or email following the screening, determination of eligibility, and telephone-consent to receive the materials according to their preference, which included IRB-approved consent forms with tagged signature and initials locations for individual male and female participants. Once the PI received the signed consents from both couple-members, each participant completed the questionnaire and demographic survey. The PI determined eligibility and if eligible, provided study paperwork and supplies, which included the protocol, a diary card, pH strips, cotton-tipped applicators, and collector forms, and study directions to the female participant in the couple.
Time Method View help for Time Method
Universe View help for Universe
Monogamous couples in the United States.
Unit(s) of Observation View help for Unit(s) of Observation
Data Type(s) View help for Data Type(s)
Mode of Data Collection View help for Mode of Data Collection
Description of Variables View help for Description of Variables
The dataset ACE contains variables related to childhood abuse.
The datasets Allele2018 and DNA_C contain variables related to cervix and fornix analysis.
The datasets Demo_combined and Phi contain demographic variables.
The datasets F_Reproductive_History and M_Reproductive_History contain variables related to the sexual health history and reproductive history of participants.
The dataset HERS contains variables related to the Hymen Estrogen Response Scale (HERS).Hide
Original Release Date View help for Original Release Date
Version History View help for Version History
2019-12-17 ICPSR data undergo a confidentiality review and are altered when necessary to limit the risk of disclosure. ICPSR also routinely creates ready-to-go data files along with setups in the major statistical software formats as well as standard codebooks to accompany the data. In addition to these procedures, ICPSR performed the following processing steps for this data collection:
- Created variable labels and/or value labels.
The public-use data files in this collection are available for access by the general public. Access does not require affiliation with an ICPSR member institution.