The Population Assessment of Tobacco and Health (PATH) Study Data User Workshop: Biomarker Restricted-Use Files

Instructor(s):

The Population Assessment of Tobacco and Health (PATH) Study is a collaboration between the National Institute on Drug Abuse, National Institutes of Health, and the Center for Tobacco Products, Food and Drug Administration (FDA). The PATH Study is a household-based, nationally representative, longitudinal cohort study of approximately 46,000 adults and youth (ages 12 and up) in the US. The Study was launched in 2011 to inform the FDA's regulatory activities under the 2009 Family Smoking Prevention and Tobacco Control Act. This workshop focuses on the Biomarker Restricted-Use Files (BRUF) from the first wave of data (Wave 1), collected from September 2013 to December 2014. Wave 1 adult respondents were asked to provide urine and blood biospecimen samples in addition to questionnaire data on tobacco use, perceptions of tobacco products, health conditions, and other topics. A subset of Wave 1 respondents had their biospecimens analyzed, generating biomarker data on exposure to nicotine and its metabolites, metals, polycyclic aromatic hydrocarbons, tobacco-specific nitrosamines, inorganic arsenic, and volatile organic compounds. These biomarker data comprise the Wave 1 BRUF.

This workshop introduces the PATH Study, including study design, data collection procedures, adult instrument, and variables. With this information, participants will be able to formulate research questions appropriate for the PATH Study biomarker data, as well as gain an understanding of the content and organization of the biomarker data files, interview data files, and weighting files. Participants will also learn how to link biomarker data files with interview data files and weighting files, as well as in working with the data and understanding the weighted results.

This workshop focuses on understanding and using PATH Study data files, not on a specific analytic approach. The workshop is a combination of lecture, discussion, and hands-on exercises.

The course is designed for academic faculty, researchers, and grad students interested in tobacco biomarkers of exposure and/or tobacco regulatory science. Participants should be comfortable with data analysis software and quantitative research methods. All examples and exercises will utilize SAS statistical software, although participants may use the software of their choice. The workshop will include 2 full days of instruction and exercises.

Prerequisites: Participants should have a basic understanding of secondary data organization and manipulation, fundamental data analysis skills, working knowledge of a statistical software package (e.g., SAS, Stata, and R) and a substantive interest in tobacco regulatory research. Previous experience with (or knowledge of) biomarkers of exposure/potential harm is recommended, but not required.

Application: Admission is competitive. Enrollment is limited. Apply through the Registration page. Provide your information, select the course, and indicate your quantitative/statistical experience and biomarker experience. Also, upload the following materials:

  • Current CV with a select list of publications. Please highlight any experience and/or coursework relevant to the PATH Study Summer Workshop, particularly prior experience with tobacco research and/or biomarker data.
  • Cover letter summarizing your research interests and experience
  • Research project description. Priority will be given to applicants with immediate interest in using the PATH Study data for tobacco regulatory research and who provide a research project description to do so. The project description should include references to theory or historical context, how the project extends what is presently known, and why the PATH Study data are needed for the project.

Fee: This workshop is free.

Application Deadline: Extended to Friday, May 25, 2018.

Course Sections