National Longitudinal Study of Adolescent Health (Add Health), 1994-2008: DNA [Restricted Use] (ICPSR 27031)

Principal Investigator(s):
Kathleen Mullan Harris, University of North Carolina-Chapel Hill; J. Richard Udry, University of North Carolina-Chapel Hill

https://doi.org/10.3886/ICPSR27031.v5

Version V5

This data collection has been deaccessioned; it is no longer distributed by ICPSR.

Additional information may be available in Collection Notes.

2014-06-30: This study has been deaccessioned and is no longer distributed by ICPSR or DSDR. More information on accessing Add Health restricted-use data can be found on the Add Health website.

The National Longitudinal Study of Adolescent Health (Add Health) is a longitudinal study of a nationally representative sample of adolescents in grades 7-12 in the United States during the 1994-1995 school year. The Add Health cohort has been followed into young adulthood with four in-home interviews, the most recent in 2008, when the sample was aged 24-32. Add Health combines longitudinal survey data on respondents' social, economic, psychological, and physical well-being with contextual data on the family, neighborhood, community, school, friendships, peer groups, and romantic relationships, providing unique opportunities to study how social environments and behaviors in adolescence are linked to health and achievement outcomes in young adulthood. The fourth wave of interviews expanded the collection of biological data in Add Health to understand the social, behavioral, and biological linkages in health trajectories as the Add Health cohort ages through adulthood. This component of the Add Health restricted data is the Wave III DNA Data File. The DNA data contain full sibling and twin DNA results. Twin and full siblings interviewed at Wave III were asked to provide saliva samples for DNA analysis. This dataset contains the genotype values for DAT1 (dopamine transporter), DRD4 (dopamine receptor), SLC6A4 (serotonin transporter), MAOA-u (monoamine oxidase A- uVNTR), DRD2 (dopamine D2 receptor), and CYP2A6 (cytochromeP450 2A6) from these samples.

The Wave IV DNA Data file contains the genotype values for DAT1 (dopamine transporter), DRD4 (dopamine D4 receptor), HTTLPR (serotonin transporter), MAOA-u (monoamine oxidase A-uVNTR), LaLgS, TRI (triallelic activity bins in 5HTTLPR), DRD2 (dopamine D2 receptor), RS4680, RS12945042, DRD5 (dopamine D5 receptor), MAOCA1 (monoamine oxidase a dinucleotide).

For more information, please see the study website.

United States Department of Health and Human Services. National Institutes of Health. Eunice Kennedy Shriver National Institute of Child Health and Human Development (P01-HD31921)

United States Department of Health and Human Services. National Institutes of Health. National Cancer Institute

United States Department of Health and Human Services. Centers for Disease Control and Prevention. Office of Minority Health and Health Disparities

United States Department of Health and Human Services. National Institutes of Health. National Institute of Nursing Research

United States Department of Health and Human Services. National Institutes of Health. Office of AIDS Research

United States Department of Health and Human Services. Centers for Disease Control and Prevention. National Center for Health Statistics

United States Department of Health and Human Services. National Institutes of Health. Office of Behavioral and Social Sciences Research

United States Department of Health and Human Services. Office of the Assistant Secretary for Planning and Evaluation

United States Department of Health and Human Services. Office of Public Health and Science. Office of Population Affairs

United States Department of Health and Human Services. National Institutes of Health. Office of Research on Women's Health

United States Department of Health and Human Services. National Institutes of Health. National Institute on Alcohol Abuse and Alcoholism

United States Department of Health and Human Services. National Institutes of Health. National Institute on Deafness and Other Communication Disorders

United States Department of Health and Human Services. Office of Public Health and Science. Office of Minority Health

United States Department of Health and Human Services. National Institutes of Health. National Institute on Drug Abuse

United States Department of Health and Human Services. National Institutes of Health. National Institute of General Medical Sciences

United States Department of Health and Human Services. National Institutes of Health. National Institute of Mental Health

National Science Foundation

academic achievement adolescents alcohol consumption birth control classroom environment dating (social) drinking behavior drug use eating habits educational environment families family planning family relationships family structure friendships health health behavior health care access health status household composition interpersonal relations living arrangements marriage neighborhood characteristics neighborhoods parent child relationship parental attitudes parental influence physical characteristics physical condition physical fitness physical limitations public assistance programs religious behavior religious beliefs reproductive history school attendance self concept self esteem sexual attitudes sexual behavior smoking social environment social networks tobacco use violence welfare services

All data in this study are restricted and are available under a Restricted Data Use Agreement.

1994 -- 2008

1994 -- 2008

2014-06-30: This study has been deaccessioned and is no longer distributed by ICPSR or DSDR. More information on accessing Add Health restricted-use data can be found on the Add Health website.

Wave I, Stage 1 School sample: stratified, random sample of all high schools in the United States. A school was eligible for the sample if it included an 11th grade and had a minimum enrollment of 30 students. A feeder school, a school that sent graduates to the high school and that included a 7th grade, was also recruited from the community. Wave I, Stage 2: An in-home sample of 27,000 adolescents was drawn consisting of a core sample from each community plus selected special over samples. Eligibility for over samples was determined by an adolescent's responses on the In-School Questionnaire. Adolescents could qualify for more than one sample. In addition, parents were asked to complete a questionnaire about family and relationships. The Wave II in-home interview sample is the same as the Wave I in-home interview sample, with a few exceptions. Information about neighborhoods/communities was gathered from a variety of previously published databases. Wave III: The in-home Wave III sample consists of Wave I respondents who could be located and re-interviewed six years later. Wave III also collected High School Transcript Release Forms as well as samples of urine and saliva.

Longitudinal

Adolescents in grades 7-12 and their families.

individual

survey data

audio computer-assisted self interview (ACASI)

record abstracts

computer-assisted personal interview (CAPI)

computer-assisted self interview (CASI)

computer-assisted telephone interview (CATI)

coded on-site observation

cognitive assessment test

face-to-face interview

paper and pencil interview (PAPI)

self-enumerated questionnaire

on-site questionnaire

telephone interview

2010-01-14

2014-06-30

2012-09-10 A second documentation file containing a descriptive report of candidate gene data included in this study has been added.

2012-01-05 Added Wave IV data and revised study title to reflect new data.

2013-11-14 Public release of documentation guides and codebooks.

2012-03-21 Some additional variables were added to pt2.

2010-01-14 ICPSR data undergo a confidentiality review and are altered when necessary to limit the risk of disclosure. ICPSR also routinely creates ready-to-go data files along with setups in the major statistical software formats as well as standard codebooks to accompany the data. In addition to these procedures, ICPSR performed the following processing steps for this data collection:

  • Performed consistency checks.
  • Standardized missing values.
  • Checked for undocumented or out-of-range codes.

2013-11-07 Part 2 Wave IV DNA was updated with the addition of new genotypes.

2013-01-29 The documentation file associated with Part 1 (Wave III DNA) was updated after a resupply of the file by the Principal Investigators. Specifically, on the fifth page of the PDF document, the rs number for DRD2 TaqIA was changed from rs1125394 to rs1800497.

2011-02-18 Title, summary, and collection dates were updated to reflect an additional data collection wave in 2008.

2010-02-04 Codebooks and documentation were made available for public download.