National Longitudinal Study of Adolescent Health (Add Health), 1994-2008: DNA [Restricted Use] (ICPSR 27031)

Version Date: Jun 30, 2014 View help for published

Principal Investigator(s): View help for Principal Investigator(s)
Kathleen Mullan Harris, University of North Carolina-Chapel Hill; J. Richard Udry, University of North Carolina-Chapel Hill

https://doi.org/10.3886/ICPSR27031.v5

Version V5

These data are no longer distributed by ICPSR.

Additional information may be available in Collection Notes.

2014-06-30: This study has been deaccessioned and is no longer distributed by ICPSR or DSDR. More information on accessing Add Health restricted-use data can be found on the Add Health website.

The National Longitudinal Study of Adolescent Health (Add Health) is a longitudinal study of a nationally representative sample of adolescents in grades 7-12 in the United States during the 1994-1995 school year. The Add Health cohort has been followed into young adulthood with four in-home interviews, the most recent in 2008, when the sample was aged 24-32. Add Health combines longitudinal survey data on respondents' social, economic, psychological, and physical well-being with contextual data on the family, neighborhood, community, school, friendships, peer groups, and romantic relationships, providing unique opportunities to study how social environments and behaviors in adolescence are linked to health and achievement outcomes in young adulthood. The fourth wave of interviews expanded the collection of biological data in Add Health to understand the social, behavioral, and biological linkages in health trajectories as the Add Health cohort ages through adulthood. This component of the Add Health restricted data is the Wave III DNA Data File. The DNA data contain full sibling and twin DNA results. Twin and full siblings interviewed at Wave III were asked to provide saliva samples for DNA analysis. This dataset contains the genotype values for DAT1 (dopamine transporter), DRD4 (dopamine receptor), SLC6A4 (serotonin transporter), MAOA-u (monoamine oxidase A- uVNTR), DRD2 (dopamine D2 receptor), and CYP2A6 (cytochromeP450 2A6) from these samples.

The Wave IV DNA Data file contains the genotype values for DAT1 (dopamine transporter), DRD4 (dopamine D4 receptor), HTTLPR (serotonin transporter), MAOA-u (monoamine oxidase A-uVNTR), LaLgS, TRI (triallelic activity bins in 5HTTLPR), DRD2 (dopamine D2 receptor), RS4680, RS12945042, DRD5 (dopamine D5 receptor), MAOCA1 (monoamine oxidase a dinucleotide).

For more information, please see the study website.

Harris, Kathleen Mullan, and Udry, J. Richard. National Longitudinal Study of Adolescent Health (Add Health), 1994-2008: DNA [Restricted Use]. Ann Arbor, MI: Carolina Population Center, University of North Carolina-Chapel Hill [distributor], Inter-university Consortium for Political and Social Research [distributor], 2014-06-30. https://doi.org/10.3886/ICPSR27031.v5

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United States Department of Health and Human Services. National Institutes of Health. Eunice Kennedy Shriver National Institute of Child Health and Human Development (P01-HD31921), United States Department of Health and Human Services. National Institutes of Health. National Cancer Institute, United States Department of Health and Human Services. National Institutes of Health. National Institute on Alcohol Abuse and Alcoholism, United States Department of Health and Human Services. National Institutes of Health. National Institute on Deafness and Other Communication Disorders, United States Department of Health and Human Services. National Institutes of Health. National Institute on Drug Abuse, United States Department of Health and Human Services. National Institutes of Health. National Institute of General Medical Sciences, United States Department of Health and Human Services. National Institutes of Health. National Institute of Mental Health, United States Department of Health and Human Services. National Institutes of Health. National Institute of Nursing Research, United States Department of Health and Human Services. National Institutes of Health. Office of AIDS Research, United States Department of Health and Human Services. National Institutes of Health. Office of Behavioral and Social Sciences Research, United States Department of Health and Human Services. National Institutes of Health. Office of Research on Women's Health, United States Department of Health and Human Services. Office of Public Health and Science. Office of Population Affairs, United States Department of Health and Human Services. Centers for Disease Control and Prevention. National Center for Health Statistics, United States Department of Health and Human Services. Centers for Disease Control and Prevention. Office of Minority Health and Health Disparities, United States Department of Health and Human Services. Office of Public Health and Science. Office of Minority Health, United States Department of Health and Human Services. Office of the Assistant Secretary for Planning and Evaluation, National Science Foundation
academic achievement   adolescents   alcohol consumption   birth control   classroom environment   dating (social)   drinking behavior   drug use   eating habits   educational environment   families   family planning   family relationships   family structure   friendships   health   health behavior   health care access   health status   household composition   interpersonal relations   living arrangements   marriage   neighborhood characteristics   neighborhoods   parent child relationship   parental attitudes   parental influence   physical characteristics   physical condition   physical fitness   physical limitations   public assistance programs   religious behavior   religious beliefs   reproductive history   school attendance   self concept   self esteem   sexual attitudes   sexual behavior   smoking   social environment   social networks   tobacco use   violence   welfare services

All data in this study are restricted and are available under a Restricted Data Use Agreement.

Carolina Population Center, University of North Carolina-Chapel Hill, Inter-university Consortium for Political and Social Research
1994 -- 2008
1994 -- 2008

2014-06-30: This study has been deaccessioned and is no longer distributed by ICPSR or DSDR. More information on accessing Add Health restricted-use data can be found on the Add Health website.

Wave I, Stage 1 School sample: stratified, random sample of all high schools in the United States. A school was eligible for the sample if it included an 11th grade and had a minimum enrollment of 30 students. A feeder school, a school that sent graduates to the high school and that included a 7th grade, was also recruited from the community. Wave I, Stage 2: An in-home sample of 27,000 adolescents was drawn consisting of a core sample from each community plus selected special over samples. Eligibility for over samples was determined by an adolescent's responses on the In-School Questionnaire. Adolescents could qualify for more than one sample. In addition, parents were asked to complete a questionnaire about family and relationships. The Wave II in-home interview sample is the same as the Wave I in-home interview sample, with a few exceptions. Information about neighborhoods/communities was gathered from a variety of previously published databases. Wave III: The in-home Wave III sample consists of Wave I respondents who could be located and re-interviewed six years later. Wave III also collected High School Transcript Release Forms as well as samples of urine and saliva.

Longitudinal

Adolescents in grades 7-12 and their families.

individual
survey data

2010-01-14

2018-02-15 The citation of this study may have changed due to the new version control system that has been implemented. The previous citation was:
  • Harris, Kathleen Mullan, and J. Richard Udry. National Longitudinal Study of Adolescent Health (Add Health), 1994-2008: DNA [Restricted Use]. ICPSR27031-v5. Chapel Hill, NC: Carolina Population Center, University of North Carolina-Chapel Hill/Ann Arbor, MI: Inter-university Consortium for Political and Social Research [distributors], 2013-11-07. http://doi.org/10.3886/ICPSR27031.v5

2013-11-14 Public release of documentation guides and codebooks.

2013-11-07 Part 2 Wave IV DNA was updated with the addition of new genotypes.

2013-01-29 The documentation file associated with Part 1 (Wave III DNA) was updated after a resupply of the file by the Principal Investigators. Specifically, on the fifth page of the PDF document, the rs number for DRD2 TaqIA was changed from rs1125394 to rs1800497.

2012-09-10 A second documentation file containing a descriptive report of candidate gene data included in this study has been added.

2012-03-21 Some additional variables were added to pt2.

2012-01-05 Added Wave IV data and revised study title to reflect new data.

2011-02-18 Title, summary, and collection dates were updated to reflect an additional data collection wave in 2008.

2010-02-04 Codebooks and documentation were made available for public download.

2010-01-14 ICPSR data undergo a confidentiality review and are altered when necessary to limit the risk of disclosure. ICPSR also routinely creates ready-to-go data files along with setups in the major statistical software formats as well as standard codebooks to accompany the data. In addition to these procedures, ICPSR performed the following processing steps for this data collection:

  • Performed consistency checks.
  • Standardized missing values.
  • Checked for undocumented or out-of-range codes.