Hawaii Aging with HIV Cardiovascular Study, 2009-2014 (ICPSR 36389)

Version Date: Mar 10, 2016

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Principal Investigator(s):
Cecilia Shikuma, University of Hawaii at Manoa. John A. Burns School of Medicine; Dominic Chow, University of Hawaii at Manoa. John A. Burns School of Medicine

https://doi.org/10.3886/ICPSR36389.v1

Version V1

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Summary

This collection has not been processed by NACDA or ICPSR, and data are released in the format provided by the principal investigators. Please report any data errors or problems to user support, and we will work with you to resolve any data-related issues.

Hawaii Aging with HIV Cardiovascular Study (HAHCS) enrolled HIV-infected volunteer adults age 40 and over, recruited from the state of Hawaii. A natural history longitudinal study, HAHCS followed a cohort of 150 HIV positive subjects for five years. The study is based on observations that, while HIV-infected individuals now live longer because of the availability of highly active antiretroviral therapy, these individuals may be at increased risk of cardiovascular (CV) morbidity and mortality. Rates of well-accepted traditional CV risk factors such as diabetes/hyperglycemia, body morphology changes and smoking are high in the HIV population. Furthermore, there is growing concern that HIV per se may also contribute to CV risk.

HAHCS evaluated the cross-sectional and longitudinal impact of oxidative stress and inflammation on the development of subclinical atherosclerosis. Researchers assessed subclinical atherosclerosis functionally by brachial artery flow mediated vasodilatation (FMD) and structurally by intima-media thickness (IMT) as well as coronary artery calcium score obtained by dual source CT. Data include behavioral health indicators, medical history information, and medical test results. Demographic data include age, sex, and race.

Citation

Shikuma, Cecilia, and Chow, Dominic. Hawaii Aging with HIV Cardiovascular Study, 2009-2014. Ann Arbor, MI: Inter-university Consortium for Political and Social Research [distributor], 2016-03-10. https://doi.org/10.3886/ICPSR36389.v1

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Funding

United States Department of Health and Human Services. National Institutes of Health. National Heart Lung and Blood Institute (5R01HL095135)

Subject Terms

Geographic Coverage

Smallest Geographic Unit

None

Distributor(s)

Inter-university Consortium for Political and Social Research
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Time Period(s)

2009-01 -- 2014-09

Date of Collection

2009 -- 2014

Data Collection Notes

  1. This collection has not been processed by ICPSR. All of the files are available as deposited by the data producer in one zipped package.

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Time Method

Longitudinal: Panel

Universe

HIV infected individuals age 40 and over living in Hawaii, receiving stable antiretroviral therapy

Data Type(s)

Presence of Common Scales

CAC, CIMT, FMD

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Original Release Date

2016-03-10

Version History

2018-02-15 The citation of this study may have changed due to the new version control system that has been implemented. The previous citation was:
  • Shikuma, Cecilia, and Dominic Chow. Hawaii Aging with HIV Cardiovascular Study, 2009-2014. ICPSR36389-v1. Ann Arbor, MI: Inter-university Consortium for Political and Social Research [distributor], 2016-03-10. http://doi.org/10.3886/ICPSR36389.v1
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Weight

None

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Notes

  • The public-use data files in this collection are available for access by the general public. Access does not require affiliation with an ICPSR member institution.