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National Longitudinal Study of Adolescent Health (Add Health), 1994-2008: DNA [Restricted Use] (ICPSR 27031) RSS

Principal Investigator(s):

Summary:

The National Longitudinal Study of Adolescent Health (Add Health) is a longitudinal study of a nationally representative sample of adolescents in grades 7-12 in the United States during the 1994-1995 school year. The Add Health cohort has been followed into young adulthood with four in-home interviews, the most recent in 2008, when the sample was aged 24-32. Add Health combines longitudinal survey data on respondents' social, economic, psychological, and physical well-being with contextual data on the family, neighborhood, community, school, friendships, peer groups, and romantic relationships, providing unique opportunities to study how social environments and behaviors in adolescence are linked to health and achievement outcomes in young adulthood. The fourth wave of interviews expanded the collection of biological data in Add Health to understand the social, behavioral, and biological linkages in health trajectories as the Add Health cohort ages through adulthood. This component of the Add Health restricted data is the Wave III DNA Data File. The DNA data contain full sibling and twin DNA results. Twin and full siblings interviewed at Wave III were asked to provide saliva samples for DNA analysis. This dataset contains the genotype values for DAT1 (dopamine transporter), DRD4 (dopamine receptor), SLC6A4 (serotonin transporter), MAOA-u (monoamine oxidase A- uVNTR), DRD2 (dopamine D2 receptor), and CYP2A6 (cytochromeP450 2A6) from these samples.

The Wave IV DNA Data file contains the genotype values for DAT1 (dopamine transporter), DRD4 (dopamine D4 receptor), HTTLPR (serotonin transporter), MAOA-u (monoamine oxidase A-uVNTR), LaLgS, TRI (triallelic activity bins in 5HTTLPR), DRD2 (dopamine D2 receptor), RS4680, RS12945042, DRD5 (dopamine D5 receptor), MAOCA1 (monoamine oxidase a dinucleotide).

For more information, please see the study website.

Series: National Longitudinal Study of Adolescent Health (Add Health), Restricted Data Series

Access Notes

  • One or more files in this study are not available for download due to special restrictions ; consult the restrictions note to learn more. You can apply online for access to the data. A login is required to apply for access.

    All data in this study are restricted and are available under a Restricted Data Use Agreement.

  • Data Sharing for Demographic ResearchThis study is maintained and distributed by Data Sharing and Demographic Research, a project funded by the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD).

Dataset(s)

DS1:  Wave III DNA
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No downloadable data files available.
DS2:  Wave IV DNA
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No downloadable data files available.

Study Description

Citation

Harris, Kathleen Mullan, and J. Richard Udry. National Longitudinal Study of Adolescent Health (Add Health), 1994-2008: DNA [Restricted Use]. ICPSR27031-v5. Chapel Hill, NC: Carolina Population Center, University of North Carolina-Chapel Hill/Ann Arbor, MI: Inter-university Consortium for Political and Social Research [distributors], 2013-11-07. doi:10.3886/ICPSR27031.v5

Persistent URL:

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Funding

This study was funded by:

  • United States Department of Health and Human Services. Centers for Disease Control and Prevention. Office of Minority Health and Health Disparities
  • United States Department of Health and Human Services. Office of Public Health and Science. Office of Minority Health
  • United States Department of Health and Human Services. Office of the Assistant Secretary for Planning and Evaluation
  • National Science Foundation
  • United States Department of Health and Human Services. National Institutes of Health. Eunice Kennedy Shriver National Institute of Child Health and Human Development (P01-HD31921)
  • United States Department of Health and Human Services. National Institutes of Health. National Cancer Institute
  • United States Department of Health and Human Services. National Institutes of Health. National Institute on Alcohol Abuse and Alcoholism
  • United States Department of Health and Human Services. National Institutes of Health. National Institute on Deafness and Other Communication Disorders
  • United States Department of Health and Human Services. National Institutes of Health. National Institute on Drug Abuse
  • United States Department of Health and Human Services. National Institutes of Health. National Institute of General Medical Sciences
  • United States Department of Health and Human Services. National Institutes of Health. National Institute of Mental Health
  • United States Department of Health and Human Services. National Institutes of Health. National Institute of Nursing Research
  • United States Department of Health and Human Services. National Institutes of Health. Office of AIDS Research
  • United States Department of Health and Human Services. National Institutes of Health. Office of Behavioral and Social Sciences Research
  • United States Department of Health and Human Services. National Institutes of Health. Office of Research on Women's Health
  • United States Department of Health and Human Services. Office of Public Health and Science. Office of Population Affairs
  • United States Department of Health and Human Services. Centers for Disease Control and Prevention. National Center for Health Statistics

Scope of Study

Methodology

Sample:   Wave I, Stage 1 School sample: stratified, random sample of all high schools in the United States. A school was eligible for the sample if it included an 11th grade and had a minimum enrollment of 30 students. A feeder school, a school that sent graduates to the high school and that included a 7th grade, was also recruited from the community. Wave I, Stage 2: An in-home sample of 27,000 adolescents was drawn consisting of a core sample from each community plus selected special over samples. Eligibility for over samples was determined by an adolescent's responses on the In-School Questionnaire. Adolescents could qualify for more than one sample. In addition, parents were asked to complete a questionnaire about family and relationships. The Wave II in-home interview sample is the same as the Wave I in-home interview sample, with a few exceptions. Information about neighborhoods/communities was gathered from a variety of previously published databases. Wave III: The in-home Wave III sample consists of Wave I respondents who could be located and re-interviewed six years later. Wave III also collected High School Transcript Release Forms as well as samples of urine and saliva.

Mode of Data Collection:   audio computer-assisted self interview (ACASI), record abstracts, computer-assisted personal interview (CAPI), computer-assisted self interview (CASI), computer-assisted telephone interview (CATI), coded on-site observation, cognitive assessment test, face-to-face interview, paper and pencil interview (PAPI), self-enumerated questionnaire, on-site questionnaire, telephone interview

Extent of Processing:  ICPSR data undergo a confidentiality review and are altered when necessary to limit the risk of disclosure. ICPSR also routinely creates ready-to-go data files along with setups in the major statistical software formats as well as standard codebooks to accompany the data. In addition to these procedures, ICPSR performed the following processing steps for this data collection:

  • Performed consistency checks.
  • Standardized missing values.
  • Checked for undocumented or out-of-range codes.

Version(s)

Original ICPSR Release:  

Version History:

  • 2013-11-14 Public release of documentation guides and codebooks.
  • 2013-11-07 Part 2 Wave IV DNA was updated with the addition of new genotypes.
  • 2013-01-29 The documentation file associated with Part 1 (Wave III DNA) was updated after a resupply of the file by the Principal Investigators. Specifically, on the fifth page of the PDF document, the rs number for DRD2 TaqIA was changed from rs1125394 to rs1800497.
  • 2012-09-10 A second documentation file containing a descriptive report of candidate gene data included in this study has been added.
  • 2012-03-21 Some additional variables were added to pt2.
  • 2012-01-05 Added Wave IV data and revised study title to reflect new data.
  • 2011-02-18 Title, summary, and collection dates were updated to reflect an additional data collection wave in 2008.
  • 2010-02-04 Codebooks and documentation were made available for public download.

Variables

Utilities

Metadata Exports

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