nmm 22 4500 ICPSR33444 MiAaI m f a u cr mn mmmmuuuu 130619s2012 miu f a eng d (MiAaI)ICPSR33444 MiAaI MiAaI Center for Education and Drug Abuse Research (CEDAR) [electronic resource] Etiological and Prospective Family Study in Southwestern Pennsylvania, Baseline Data, 1990-2011 Ralph E. Tarter 2012-08-10 Ann Arbor, Mich. Inter-university Consortium for Political and Social Research [distributor] 2012 ICPSR 33444 Numeric Title from ICPSR DDI metadata of 2013-06-19. AVAILABLE. This study is freely available to the general public. Also available as downloadable files. The Center for Education and Drug Abuse Research (CEDAR) conducts research on 775 families enrolled in the Center's prospective investigations into the etiology of substance use disorder (SUD). The pro-bands are men with lifetime presence/absence of SUD consequent to use of an illicit drug who have a 10-12 year old biological son or daughter. The biological children of SUD men are assigned to the high average risk (HAR) group whereas offspring of men without SUD, having neither axis 1 disorder ("normal") nor SUD psychiatric disorder, are assigned to the low average risk (LAR) group. A second control group (Psych control) was also collected, in whom the fathers had a lifetime DSM-III-R diagnosis of any psychiatric disorder not related to substance use. The sample sizes are as follows: HAR = 344, LAR = 350, and Psych = 81. The children are currently in varying stages of follow-up evaluation conducted at ages 12-14, 16, 19, and annually thereafter until age 30. CEDAR has already shown that they can predict in 10-12 year old youth cannabis use disorder by age 22 with approximately 70 percent accuracy, thereby substantiating the paradigm, subject recruitment strategy, and measurement protocols. Multidisciplinary research is conducted on family members (father, mother, children) with the objective of elucidating the genetic, bio-behavioral, and environmental factors on development of SUD consequent to use of illegal drugs. Research protocols are organized into three thematically connected research modules (Neurogenetics, Developmental Psychopathology, and Translation) linking etiology and prevention. The research components thus align with the NIH Roadmap model such that basic science informs clinical research leading to prevention guided by an understanding of etiology. In addition to module-level research, faculty also participate in three organizational aims: (1) Devise a practical scale to quantify the transmissible liability to SUD; (2) Empirically test a bio-psychological theory of SUD etiology focusing on off-time maturation leading to psychological dysregulation predisposing to SUD; and, (3) Delineate SUD liability variants within an ontogenetic framework. Cf.: http://dx.doi.org/10.3886/ICPSR33444.v1 families icpsr family relations icpsr health icpsr mental health icpsr parent child relationship icpsr parents icpsr participation icpsr personality assessment icpsr psychiatric services icpsr psychological evaluation icpsr psychological wellbeing icpsr psychosocial assessment icpsr social attitudes icpsr social behavior icpsr social life icpsr substance abuse icpsr aptitude icpsr attitudes icpsr child health icpsr children icpsr cognition icpsr cognitive functioning icpsr domestic relations icpsr drug abuse icpsr drug use icpsr ICPSR XVII.H. Social Institutions and Behavior, Family and Gender ICPSR XVII.C.1. Social Institutions and Behavior, Socialization, Students, and Youth, United States NAHDAP I. National Addiction and HIV Data Archive Program Tarter, Ralph E. Inter-university Consortium for Political and Social Research. ICPSR (Series) 33444 Access restricted ; authentication may be required: http://dx.doi.org/10.3886/ICPSR33444.v1